Savage N W, Adkins K F, Weir A V, Grundy G E
J Oral Pathol. 1986 Apr;15(4):209-12. doi: 10.1111/j.1600-0714.1986.tb00609.x.
The clinical and radiographic features of a group of apical periodontal cysts associated with endodontically treated deciduous molar teeth have been previously reported. The histological description and histochemical investigation of distinctive intraepithelial inclusions are described in this paper. The chronic inflammatory response is dominated by plasma cells and the wall contains an amorphous, eosinophilic material that is shown to contain phenolic groupings similar to those present in the intracanal medicaments used clinically. A direct relationship is proposed between the inclusions, continued antigenic stimulation within the lesions and their clinical behaviour.
先前已有报道一组与经牙髓治疗的乳磨牙相关的根尖牙周囊肿的临床和影像学特征。本文描述了独特的上皮内包涵体的组织学描述和组织化学研究。慢性炎症反应以浆细胞为主，囊壁含有一种无定形的嗜酸性物质，已证明其含有与临床使用的根管内药物中存在的酚类基团相似的酚类基团。文中提出了包涵体、病变内持续的抗原刺激与其临床行为之间的直接关系。
