Sokouti Mohsen, Golzari Samad Ej, Pezeshkian Masoud, Farahnak Mohammad-Reza
Department of Cardiothoracic Surgery, Tabriz University of Medical Sciences, Tabriz, Iran.
J Cardiovasc Thorac Res. 2013;5(1):11-6. doi: 10.5681/jcvtr.2013.003. Epub 2013 Mar 14.
Postoperative stenosis and dysphagia after esophageal carcinoma resection is the major problem. The aim of this study is to compare two types cervical esophagogastric anastomosis in reduction of stricture formation in esophageal cancer surgery.
The subjects of this study were 223 patients undergoing esophageal carcinoma resection during 1998 to 2007. Twenty two patients were excluded from the study because of recurrent malignancy of anastomosis, mortality and losing in follow up period. Two hundred and one patients remained by the end of study were classified into two groups: 98 patients were treated by routinely transverse hand-sewn cervical esophagogastric anastomosis (group 1); and 103 patients were treated by the proposed oblique hand-sewn esophagogastric anastomotic technique (group 2). All the operations were with high abdominal and left cervical incisions (Transhiatal esophagectomy). All patients of both groups were followed up at least 6-month for detection of anastomotic strictures.
Postoperative dysphagia occurred in 20 patients of group 1 versus 5 patients of group 2. In working up by rigid esophagoscopy, two patients of group 2 and four patients of group 1 had not true strictures. Anastomotic strictures occurred in 16 cases of group 1, versus 3 cases of group 2. Statistical comparative analysis results of two groups about stricture formation were significant (3% versus 16% P= 0.003).
The oblique hand-sewn esophagogastric anastomostic techniques reduce markedly the rate of stricture formation after esophagectomy.
食管癌切除术后的吻合口狭窄和吞咽困难是主要问题。本研究的目的是比较两种类型的颈部食管胃吻合术在减少食管癌手术中狭窄形成方面的效果。
本研究的对象为1998年至2007年期间接受食管癌切除术的223例患者。22例患者因吻合口复发恶性肿瘤、死亡及失访而被排除在研究之外。研究结束时,剩余的201例患者被分为两组:98例患者接受常规横向手工缝合颈部食管胃吻合术(第1组);103例患者接受改良的斜向手工缝合食管胃吻合技术(第2组)。所有手术均采用高腹部和左颈部切口(经胸食管切除术)。两组所有患者均至少随访6个月以检测吻合口狭窄情况。
第1组有20例患者术后出现吞咽困难,而第2组有5例。在通过硬式食管镜检查时,第2组有2例患者和第1组有4例患者没有真正的狭窄。第1组有16例发生吻合口狭窄,而第2组有3例。两组关于狭窄形成的统计学比较分析结果具有显著性差异(3%对16%,P = 0.003)。
斜向手工缝合食管胃吻合技术显著降低了食管切除术后狭窄形成的发生率。