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进行性四肢瘫的一个不寻常病因。

An unusual cause of progressive quadriparesis.

作者信息

Upreti Vimal, Sridhar M S, Dhull Pawan, Sen Arijit

机构信息

Department of Endocrinology, Command Hospital (Air Force), Bangalore, Karnataka, India.

出版信息

Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S155-6. doi: 10.4103/2230-8210.119555.

DOI:10.4103/2230-8210.119555
PMID:24251141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3830287/
Abstract

Thyroid carcinoma is a rare cause of compressive myelopathy. Quadriparesis as the presenting manifestation of follicular carcinoma of thyroid without any preceding features of malignancy is quite uncommon. We describe a case of a 55-year-old woman who presented with progressive quadriparesis of 2 months duration, on evaluation was found to have a large tumor destroying C1, C2 vertebrae and occupying craniovertebral junction. Histopathological examination of excised tumor was follicular thyroid carcinoma. She was successfully managed with surgical excision, stabilization of spine followed by radiotherapy.

摘要

甲状腺癌是导致压迫性脊髓病的罕见病因。以四肢瘫作为甲状腺滤泡癌的首发表现且无任何先前恶性特征的情况相当少见。我们报告一例55岁女性，她出现了持续2个月的进行性四肢瘫，经评估发现有一个大肿瘤破坏了C1、C2椎体并占据了颅颈交界区。切除肿瘤的组织病理学检查为甲状腺滤泡癌。她通过手术切除、脊柱稳定术随后进行放疗得到了成功治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/358c/3830287/f0c4c38956eb/IJEM-17-155-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/358c/3830287/d09118751d94/IJEM-17-155-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/358c/3830287/22f8ee661ff2/IJEM-17-155-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/358c/3830287/f0c4c38956eb/IJEM-17-155-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/358c/3830287/d09118751d94/IJEM-17-155-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/358c/3830287/22f8ee661ff2/IJEM-17-155-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/358c/3830287/f0c4c38956eb/IJEM-17-155-g003.jpg

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引用本文的文献

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本文引用的文献

1
Approach to the thyroid cancer patient with extracervical metastases.甲状腺癌伴颈部外转移患者的处理方法。
J Clin Endocrinol Metab. 2010 Mar;95(3):987-93. doi: 10.1210/jc.2009-2305.
2
Bone metastases from differentiated thyroid carcinoma.分化型甲状腺癌的骨转移
Endocr Relat Cancer. 2008 Mar;15(1):37-49. doi: 10.1677/ERC-07-0229.
3
Bone metastases from thyroid carcinoma: a histopathologic study with clinical correlates.甲状腺癌骨转移：一项具有临床相关性的组织病理学研究。
Arch Pathol Lab Med. 2000 Oct;124(10):1440-7. doi: 10.5858/2000-124-1440-BMFTC.