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前列腺癌继发齿状突病理性骨折导致的痉挛性四肢瘫:一种罕见的表现。

Spastic quadriparesis due to pathological fracture of odontoid secondary to carcinoma prostate: A rare presentation.

作者信息

Gill Maneet, Swamy M N, Maheshwari Vikas, Lingaraju T S, Mukherjee Aishik

机构信息

Department of Neurosurgery, Armed Forces Medical College, Pune, Maharashtra, India.

出版信息

J Craniovertebr Junction Spine. 2017 Apr-Jun;8(2):153-155. doi: 10.4103/0974-8237.208045.

Abstract

Prostate carcinoma presenting as symptomatic metastases to atlantoaxial spine is extremely rare. Spastic quadriparesis due to pathological fracture of odontoid as the only initial manifestation without symptoms of primary malignancy is rarer still. We report a 64-year-old male who presented with progressive spastic quadriparesis along with urinary retention of 3 weeks duration. Computed tomography and magnetic resonance imaging cervical spine and craniovertebral junction showed type III pathological fracture of odontoid with anterior translation of C1 with spinal cord compression. Biopsy from an enlarged prostate showed adenocarcinoma of prostate. The patient was managed conservatively from neurological aspect as he refused for any surgical intervention.

摘要

以寰枢椎有症状转移为表现的前列腺癌极为罕见。因齿状突病理性骨折导致的痉挛性四肢瘫,作为唯一的初始表现且无原发性恶性肿瘤症状的情况更为罕见。我们报告一例64岁男性,其表现为进行性痉挛性四肢瘫伴3周的尿潴留。颈椎和颅颈交界区的计算机断层扫描和磁共振成像显示齿状突III型病理性骨折,C1向前移位并压迫脊髓。前列腺增大处活检显示为前列腺腺癌。由于患者拒绝任何手术干预,从神经学角度对其进行了保守治疗。

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