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一名甲状旁腺功能减退患者因骨化三醇和碳酸氢钙诱发的乳碱综合征。

Milk alkali syndrome induced by calcitriol and calcium bicarbonate in a patient with hypoparathyroidism.

作者信息

Altun Eda, Kaya Bülent, Paydaş Saime, Balal Mustafa

机构信息

Department of Nephrology, Faculty of Medicine, Cukurova University, Adana 01130, Turkey.

出版信息

Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S191-3. doi: 10.4103/2230-8210.119568.

Abstract

The milk-alkali syndrome (MAS) was a common cause of hypercalcemia, metabolic alkalosis, and renal failure in the early 20(th) century. This syndrome was first recognized secondary to treatment of peptic ulcer disease with milk and absorbable alkali. Its incidence fell after the introduction of H2-blocker and proton pump inhibitor. Persistent ingestion of calcium carbonate and vitamin D caused MAS. We report a patient presenting with a triad of hypercalcemia, metabolic alkalosis and renal failure secondary to treatment of idiopathic hypoparathyroidism.

摘要

乳-碱综合征(MAS)在20世纪早期是高钙血症、代谢性碱中毒和肾衰竭的常见病因。该综合征最初被认为是由于用牛奶和可吸收碱治疗消化性溃疡疾病所致。在引入H2受体阻滞剂和质子泵抑制剂后,其发病率有所下降。持续摄入碳酸钙和维生素D会导致MAS。我们报告一例因特发性甲状旁腺功能减退症治疗继发出现高钙血症、代谢性碱中毒和肾衰竭三联征的患者。

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