Tuon F F, Nihei C H, Gryschek R C, Seguro A C
Department of Infectious and Parasitic Diseases, School of Medicine, University of Sao Paulo, Brazil.
Int J STD AIDS. 2008 Feb;19(2):137-8. doi: 10.1258/ijsa.2007.007161.
Hypercalcaemia in patients with HIV infection is usually associated with specific conditions such as lymphoma and granulomatous diseases. We described a case of severe hypercalcaemia consequent to vitamin D intoxication and secondary renal failure in a HIV patient under tenofovir using. Serum creatinine and calcium returned to near normal levels after vitamin D discontinuation, saline and furosemide administration. Some aspects of the drug-induced nephropathy are discussed.
感染人类免疫缺陷病毒（HIV）的患者出现高钙血症通常与特定疾病相关，如淋巴瘤和肉芽肿性疾病。我们描述了一例在接受替诺福韦治疗的HIV患者中，因维生素D中毒及继发性肾衰竭导致严重高钙血症的病例。停用维生素D、给予生理盐水和呋塞米后，血清肌酐和钙水平恢复至接近正常。本文讨论了药物性肾病的一些方面。
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