Sundmacher R
Klin Monbl Augenheilkd. 1986 Apr;188(4):307-9. doi: 10.1055/s-2008-1050636.
Traumatogenic herpetic eye disease may be initiated via several pathophysiologic pathways. Trauma of the trigeminal ganglion or adequate systemic alterations are the most effective means of destabilizing ganglionic latency of the herpesvirus with consequent neuronal peripheral virus shedding. Peripheral stimuli seem to have far less effect on ganglionic latency--at least in man. The authors report on a rare case of proven herpetic primary disease. The trigger was probably a small intrastromal foreign body which caused an unusual alteration of the cornea with long-standing healing disorders.
创伤性疱疹性眼病可能通过多种病理生理途径引发。三叉神经节损伤或适当的全身改变是破坏疱疹病毒神经节潜伏状态并导致神经元外周病毒脱落的最有效手段。外周刺激对神经节潜伏状态的影响似乎要小得多——至少在人类中是这样。作者报告了一例经证实的疱疹原发性疾病的罕见病例。触发因素可能是一个小的基质内异物，它导致角膜出现异常改变并伴有长期愈合障碍。
