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早产儿儿童和青少年的肥胖问题:儿科门诊随访。

Obesity in prematurely born children and adolescents: follow up in pediatric clinic.

机构信息

Department of Pediatrics, Texas Tech University Health Sciences Center, Amarillo, Texas, USA.

出版信息

Nutr J. 2013 Nov 19;12(1):150. doi: 10.1186/1475-2891-12-150.

Abstract

BACKGROUND

Understanding associated risk for obesity is a prerequisite to develop early life interventions to arrest the increasing epidemic of metabolic syndrome and obesity among preterm born children and adolescents.

FINDINGS

A retrospective review of 160 charts was conducted to determine the associated risk of being obese during childhood and adolescent period in preterm children. Birth weight, gestational age, weight gain, demographics, maternal health, socioeconomics, and clinical factors during early neonatal life were evaluated. The number of obese children increased with age and was observed more in the adolescent population. Obese children were significantly heavier at age 24 months old compared to their peers (p = 0.001). Analysis of associated risk for maternal demographics, maternal age, maternal marital status or race, prenatal factors, maternal substance abuse or diabetes, neonatal factors, weight for gestational age or birth weight did not show any statistically significant risk for future obesity. Duration of gestational age (OR 1.6; p = 0.017) and heavier birth weight (OR 3.2; p = 0.001) were associated with risk of obesity.

CONCLUSION

Among preterm born babies in the study, the highest risk of developing excessive weight during childhood and adolescent periods are babies born at more advanced gestational age. Strong positive association was found between birth weight and body weight in childhood. By 24 months old, there was a distinguished group of toddlers, who were heavier than their peers and remained with excessive weight as they got older. Primary care pediatricians should draw attention to premature babies, overweight infants and toddlers.

摘要

背景

了解肥胖相关风险是制定早期生活干预措施的前提,以阻止代谢综合征和肥胖症在早产儿及青少年中的流行。

发现

本研究回顾性分析了 160 份病历,以确定早产儿在儿童和青少年期肥胖的相关风险。评估了出生体重、胎龄、体重增加、人口统计学、母亲健康、社会经济状况和新生儿期的临床因素。肥胖儿童的数量随年龄增长而增加,在青少年人群中更为明显。与同龄人相比,肥胖儿童在 24 个月大时体重明显更重(p=0.001)。对母亲人口统计学、母亲年龄、母亲婚姻状况或种族、产前因素、母亲药物滥用或糖尿病、新生儿因素、胎龄或出生体重与体重相关的分析并没有显示出任何与未来肥胖相关的统计学风险。胎龄持续时间(OR 1.6;p=0.017)和较高的出生体重(OR 3.2;p=0.001)与肥胖风险相关。

结论

在本研究的早产儿中,在儿童和青少年时期发展为超重的风险最高的是胎龄较长的婴儿。出生体重与儿童期体重之间存在很强的正相关关系。到 24 个月大时,有一群明显超重的幼儿,他们比同龄人更重,随着年龄的增长体重仍然超重。初级保健儿科医生应关注早产儿、超重婴儿和幼儿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c77/3842808/9ce32f91018a/1475-2891-12-150-1.jpg

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