Morace G, Amalfitano G, Polonelli L
Mycopathologia. 1986 Apr;94(1):53-7. doi: 10.1007/BF00437262.
Ascites fluid from hybridoma cell lines producing monoclonal antibodies to an exoantigen of Microsporum canis was assayed for its precipitating properties. Three types of monoclonal antibodies were used for serological analysis of heterologous mycelial cultures. Based on specific antigenic determinants, the fungal strains showed different immunodiffusion reactivity within the species. The monoclonal antibodies also proved to be effective reagents for serotyping heterogeneous species. They may also have potential applications in epidemiology.
对来自产生针对犬小孢子菌外抗原的单克隆抗体的杂交瘤细胞系的腹水进行沉淀特性分析。使用三种类型的单克隆抗体对异源菌丝体培养物进行血清学分析。基于特定的抗原决定簇，真菌菌株在种内表现出不同的免疫扩散反应性。这些单克隆抗体也被证明是对异源菌种进行血清分型的有效试剂。它们在流行病学中也可能有潜在应用。
