Stanislawczuk Rodrigo, Pereira Fabiane, Muñoz Miguel Angel, Luque Issis, Farago Paulo Vitor, Reis Alessandra, Loguercio Alessandro D
Department of Restorative Dentistry, State University of Ponta Grossa, Ponta Grossa, Brazil; Department of Restorative, Dentistry, Center of High Education of Campos Gerais, Ponta Grossa, Brazil.
Department of Restorative Dentistry, State University of Ponta Grossa, Ponta Grossa, Brazil.
J Dent. 2014 Jan;42(1):39-47. doi: 10.1016/j.jdent.2013.11.002. Epub 2013 Nov 16.
This study evaluated the effect of addition of diacetate CHX in different concentrations into two simplified etch-and-rinse (ER) adhesive systems (XP Bond [XP] and Ambar {AM}) on the ultimate tensile strength (UTS), degree of conversion (DC), 60-day cumulative water sorption (WS), solubility (SO) and CHX release (CR) as well as the immediate (IM) and 1-year (1Y) resin-dentine bond strength (μTBS) and nanoleakage (NL).
Ten experimental adhesive systems were formulated according to the addition of CHX diacetate (0 [control], 0.01, 0.05, 0.1 and 0.2%) in the two ER. For UTS and DC, specimens were constructed and tested after 24h. For WS, SO and CR, after specimens build-up, they were stored in water and the properties measured after 60 days. The occlusal enamel of fifty molars was removed and the adhesives were applied in dentine surface after 37% phosphoric acid etching. After composite resin build-ups, specimens were longitudinally sectioned to obtain resin-dentine bonded sticks (0.8mm(2)). Specimens were tested in tension at 0.5mm/min in the IM or 1Y. For NL, 2 bonded sticks from each tooth were prepared and analyzed under SEM. The data were submitted to appropriate statistical analysis (α=0.05).
The addition of CHX did not influence UTS, DC, WS and SO (p<0.05). Higher CR was observed in adhesives with higher concentration of CHX (p<0.05). After 1Y, significant reductions of μTBS and increases of NL were observed in the control groups (p<0.05). Reductions of μTBS and increase of NL over time were not observed (AM) for CHX-containing adhesives or it was less pronounced than the control (XP) regardless of the CHX concentration.
The addition of CHX diacetate in concentrations until 0.2% in the simplified ER adhesive systems may be an alternative to increase the long-term stability of resin-dentine interfaces, without jeopardizing the adhesives' mechanical properties evaluated.
本研究评估了在两种简化酸蚀冲洗（ER）粘结系统（XP Bond [XP]和Ambar {AM}）中添加不同浓度的二醋酸氯己定（CHX）对极限拉伸强度（UTS）、转化率（DC）、60天累积吸水率（WS）、溶解度（SO）和CHX释放率（CR）的影响，以及即时（IM）和1年（1Y）树脂-牙本质粘结强度（μTBS）和纳米渗漏（NL）。
根据在两种ER粘结系统中添加二醋酸氯己定（0 [对照组]、0.01%、0.05%、0.1%和0.2%）配制10种实验性粘结系统。对于UTS和DC，在24小时后制备并测试样本。对于WS、SO和CR，在样本制备完成后，将其置于水中储存，60天后测量相关性能。去除50颗磨牙的咬合面釉质，在37%磷酸酸蚀后将粘结剂应用于牙本质表面。复合树脂充填后，将样本纵向切片以获得树脂-牙本质粘结棒（0.8mm(2)）。在即时或1年时，以0.5mm/min的速度对样本进行拉伸测试。对于NL，从每颗牙齿制备2根粘结棒并在扫描电子显微镜下进行分析。数据进行适当的统计分析（α = 0.05）。
添加CHX对UTS、DC、WS和SO没有影响（p < 0.05）。在CHX浓度较高的粘结剂中观察到较高的CR（p < 0.05）。1年后，对照组的μTBS显著降低，NL增加（p <0.05）。对于含CHX的粘结剂，未观察到μTBS随时间降低和NL增加（AM），或者无论CHX浓度如何，其变化程度均不如对照组（XP）明显。
在简化的ER粘结系统中添加浓度直至0.2%的二醋酸氯己定，可能是提高树脂-牙本质界面长期稳定性的一种替代方法，且不会损害所评估的粘结剂的机械性能。
