Department of Entomology, Iowa State University, 50011, Ames, IA, USA.
Theor Appl Genet. 1985 Aug;70(5):491-6. doi: 10.1007/BF00305981.
A FORTRAN program was written that calculates composite linkage disequilibrium coefficients from genotypic data. Chi-square tests determine whether coefficients calculated for allele and locus pairs are significantly greater than zero. A subroutine is provided that partitions the variance in linkage disequilibrium into within- and between-subpopulation components. Output obtained from analysis of allozyme data collected from natural subpopulations of the house fly (Musca domestica L.) are included to illustrate features of the program.
我们编写了一个 FORTRAN 程序，用于根据基因型数据计算复合连锁不平衡系数。卡方检验用于确定计算得到的等位基因和基因座对的系数是否显著大于零。程序还提供了一个将连锁不平衡方差划分为亚群内和亚群间成分的子程序。我们分析了从家蝇（Musca domestica L.）自然亚群中收集的同工酶数据，并包含了输出结果，以说明程序的特点。
