Mol Reprod Dev. 2014 Jan;81(1):84-6. doi: 10.1002/mrd.22284.
It is estimated that 20% of couples are infertile, and half of these infertility cases are linked to men. One of conditions that can affect male fertility is asthenozoospermia. We applied Raman spectroscopy to the analysis of the metabolome of the human seminal plasma, and used chemometrics on the patterns of Raman spectra obtained. Significant changes were observed in the metabolome of the human seminal plasma of asthenozoospermic patients.
据估计，有 20%的夫妇患有不孕症，其中一半的不孕病例与男性有关。会影响男性生育能力的病症之一是弱精症。我们应用拉曼光谱分析了人类精液的代谢组学，并对获得的拉曼光谱模式进行了化学计量学分析。在弱精症患者的人类精液代谢组中观察到了显著的变化。
