Notter O
Fortschr Neurol Psychiatr Grenzgeb. 1977 Aug;45(8):429-40.
This paper reports 2 cases of the Tolosa-Hunt Syndrome and reviews 70 other cases reported in the literature. Common findings of this syndrome are the recurring painful ophthalmoplegia affecting the 3rd, 4th and 6th cranial nerve, as well as the first branch of the 5th and the optic nerve. No ethiologic factor has so far been found, but is regarded as a non specific inflammation in the area of the sinus cavernosus and adjacent orbital bone. Residual defects in about one third of affected persons is the normal course of the disease. Early diagnosis and initiation of steroid therapy results in quick relief of pain and may influence prognosis.
本文报告了2例托洛萨-亨特综合征,并回顾了文献中报道的其他70例病例。该综合征的常见表现为反复出现的疼痛性眼肌麻痹,累及第3、4、6颅神经,以及第5颅神经的第一分支和视神经。目前尚未发现病因,但被认为是海绵窦及相邻眶骨区域的非特异性炎症。约三分之一的患者会出现残留缺陷,这是该病的正常病程。早期诊断并开始使用类固醇治疗可迅速缓解疼痛,并可能影响预后。