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Response to "Ethnic-specific in vitro-in vivo extrapolation and physiologically based pharmacokinetic approaches to predict cytochrome P450-mediated pharmacokinetics in Chinese population: opportunities and challenges".

作者信息

Barter Zoe E, Tucker Geoffrey T, Rowland-Yeo Karen

机构信息

Simcyp Limited (a Certara company), Blades Enterprise Centre, John Street, Sheffield, S2 4SU, UK,

出版信息

Clin Pharmacokinet. 2014 Feb;53(2):203. doi: 10.1007/s40262-013-0118-x.

DOI:10.1007/s40262-013-0118-x
PMID:24255012
Abstract
摘要

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本文引用的文献

1
Ethnic-specific in vitro-in vivo extrapolation and physiologically based pharmacokinetic approaches to predict cytochrome P450-mediated pharmacokinetics in the Chinese population: opportunities and challenges.基于种族特异性的体外-体内外推法和生理药代动力学方法预测中国人群中细胞色素P450介导的药代动力学：机遇与挑战
Clin Pharmacokinet. 2014 Feb;53(2):197-202. doi: 10.1007/s40262-013-0119-9.
2
Differences in cytochrome p450-mediated pharmacokinetics between chinese and caucasian populations predicted by mechanistic physiologically based pharmacokinetic modelling.基于机制的生理药代动力学模型预测中国人与高加索人群细胞色素 P450 介导的药代动力学差异。
Clin Pharmacokinet. 2013 Dec;52(12):1085-100. doi: 10.1007/s40262-013-0089-y.
3
Evaluating a physiologically based pharmacokinetic model for prediction of omeprazole clearance and assessing ethnic sensitivity in CYP2C19 metabolic pathway.
评估基于生理的药代动力学模型以预测奥美拉唑清除率并评估CYP2C19代谢途径中的种族敏感性。
Eur J Clin Pharmacol. 2015 May;71(5):617-24. doi: 10.1007/s00228-015-1834-y. Epub 2015 Mar 24.
Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: polymorphism in RFLP and DNA sequence of CYP2D6.
中国人群中异喹胍羟基化遗传变异的分子基础：CYP2D6的限制性片段长度多态性及DNA序列多态性
Clin Pharmacol Ther. 1993 Apr;53(4):410-8. doi: 10.1038/clpt.1993.44.
4
Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.
Mol Pharmacol. 1994 Sep;46(3):452-9.