超声触发的可注射纳米网络调控血糖水平。
Ultrasound-triggered regulation of blood glucose levels using injectable nano-network.
机构信息
Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, NC, 27695, USA.
出版信息
Adv Healthc Mater. 2014 Jun;3(6):811-6. doi: 10.1002/adhm.201300490. Epub 2013 Nov 19.
Abstract
The integration of an injectable insulin-encapsulated nano-network with a focused ultrasound system (FUS) can remotely regulate insulin release both in vitro and in vivo. A single subcutaneous injection of the nano-network with intermittent FUS administration facilitates reduction of the blood glucose levels in type 1 diabetic mice for up to 10 d.
摘要
将可注射的胰岛素包封纳米网络与聚焦超声系统 (FUS) 集成，可以在体外和体内远程调节胰岛素释放。单次皮下注射纳米网络并间歇性给予 FUS 治疗，可使 1 型糖尿病小鼠的血糖水平在 10 天内持续降低。
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