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芬兰北部唇腭裂的描述性流行病学研究。

A descriptive epidemiology study of cleft lip and palate in Northern Finland.

作者信息

Lithovius Riitta H, Ylikontiola Leena P, Harila Virpi, Sándor George K

机构信息

Department of Oral and Maxillofacial Surgery, Institute of Dentistry, University of Oulu, Oulu Cleft Lip and Palate Center, Oulu University Hospital , Oulu , Finland.

出版信息

Acta Odontol Scand. 2014 Jul;72(5):372-5. doi: 10.3109/00016357.2013.840737. Epub 2013 Nov 21.

Abstract

OBJECTIVE

The aim of this study was to determine the incidence of cleft lip and/or cleft palate in a population uniquely from Northern Finland.

MATERIALS AND METHODS

The records of a total of 214 cleft patients treated between 1998-2011 at the Oulu Cleft Lip and Palate Center at the University of Oulu were assessed on a retrospective basis. Data regarding cleft type, sex and side of cleft was collected and analyzed. Family history of clefting was investigated.

RESULTS

Cleft palate (68.7%) was most frequently found, followed by cleft lip and palate (18.7%) and cleft lip with or without alveolus (12.6%). Cleft palate occurred more frequently in females (63.3%) and cleft lip and palate was more frequently found in males (62.5%). The left side was more frequently affected in both male and female patients. Left-sided clefts were observed in 82% of patients compared to right-sided clefts in 18%. A family history of clefting was detected in 20.1% of patients.

CONCLUSION

The incidence of clefts in Northern Finland is higher than the corresponding incidence in other European countries. Cleft palate was the most frequent cleft type and it was more frequent in females. In males, cleft lip and palate was more frequent. The left side was more frequently affected in both genders. One fifth of the patients had a family history of clefts.

摘要

目的

本研究的目的是确定仅来自芬兰北部人群中唇裂和/或腭裂的发病率。

材料与方法

对1998年至2011年间在奥卢大学唇腭裂中心接受治疗的总共214例腭裂患者的记录进行回顾性评估。收集并分析有关腭裂类型、性别和腭裂侧别的数据。调查腭裂家族史。

结果

最常发现的是腭裂(68.7%),其次是唇腭裂(18.7%)和伴有或不伴有牙槽突的唇裂(12.6%)。腭裂在女性中更常见(63.3%),唇腭裂在男性中更常见(62.5%)。男性和女性患者中左侧受累更频繁。82%的患者观察到左侧腭裂,而右侧腭裂为18%。20.1%的患者检测到腭裂家族史。

结论

芬兰北部腭裂的发病率高于其他欧洲国家的相应发病率。腭裂是最常见的腭裂类型,在女性中更常见。在男性中,唇腭裂更常见。男女两侧受累均以左侧更频繁。五分之一的患者有腭裂家族史。

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