Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139 United States.
J Am Chem Soc. 2013 Dec 11;135(49):18497-501. doi: 10.1021/ja4079094. Epub 2013 Nov 20.
A continuous method for the formation of cyclic carbonates from epoxides and carbon dioxide (CO2) is described. The catalysts used are inexpensive and effective in converting the reagents to the products in a residence time (t(R)) of 30 min. The cyclic carbonate products are obtained in good to excellent yield (51-92%). On the basis of a series of kinetics experiments, we propose a reaction mechanism involving epoxide activation by electrophilic bromine and CO2 activation by an amide.
一种由环氧丙烷和二氧化碳（CO2）连续合成环状碳酸酯的方法。所使用的催化剂廉价且高效，在 30 分钟的停留时间（t(R)）内将试剂转化为产物。环状碳酸酯产物的收率为 51-92%。基于一系列动力学实验，我们提出了一种反应机理，涉及溴的亲电活化环氧丙烷和酰胺的 CO2 活化。
