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使用Onyx 18对天幕硬脑膜动静脉瘘进行经动脉栓塞术

Transarterial embolization of tentorial dural arteriovenous fistulas with onyx 18.

作者信息

Lv Xianli, Jiang Chuhan, Li Youxiang, Yang Xinjian, Wu Zhongxue

机构信息

Beijing Neurosurgical institute, Beijing, the People's Republic of China - Beijing Tiantan Hospital, Capital Medical University, Beijing, the People's Republic of China -

出版信息

Neuroradiol J. 2008 Jun 3;21(3):406-14. doi: 10.1177/197140090802100318.

Abstract

Dural arteriovenous fistulas (DVAFs) have been reported to be treated transarterially with Onyx 18. We present a series of tentorial DAVFs treated by transarterial embolization with Onyx 18 over an 18-month period. Eight patients with tentorial DAVFs were treated between September 2005 and February 2007. All patients were treated transarterially with Onyx 18. The clinical presentation, treatment strategies and results were studied. Eight patients presented with intracranial hemorrhage or progressive neurological deficits. Retrograde leptomeningeal venous drainage was documented in every patient, classifying the lesions as Cognard Type IV. Post treatment angiography demonstrated complete obliteration in six cases. Clinical follow up ranged from six to 14 months. One patient experienced neurological decline after endovascular treatment and exhibited clinical improvement. There were no episodes of rehemorrhage or new neurological deficits. Outcomes were excellent in seven patients, fair in one case. Transarterial embolization of tentorial DAVF is feasible and may result in complete occlusion of the fistulous connection with liquid nonadhesives.

摘要

据报道,硬脑膜动静脉瘘(DVAFs)可通过经动脉注射Onyx 18进行治疗。我们报告了一系列在18个月期间经动脉用Onyx 18栓塞治疗的天幕硬脑膜动静脉瘘(DAVFs)。2005年9月至2007年2月期间,对8例天幕DAVFs患者进行了治疗。所有患者均经动脉用Onyx 18治疗。对临床表现、治疗策略及结果进行了研究。8例患者表现为颅内出血或进行性神经功能缺损。所有患者均记录有逆行性软脑膜静脉引流,将病变分类为Cognard IV型。治疗后血管造影显示6例完全闭塞。临床随访时间为6至14个月。1例患者在血管内治疗后出现神经功能减退,但随后临床症状改善。未发生再出血或新的神经功能缺损事件。7例患者预后良好,1例患者预后一般。经动脉栓塞天幕DAVF是可行的,且可能通过液体非粘性材料使瘘口完全闭塞。

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