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胰头癌的姑息治疗

Palliation for carcinoma of head of pancreas.

作者信息

Ubhi C S, Doran J

出版信息

Ann R Coll Surg Engl. 1986 May;68(3):159-62.

PMID:2425694
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2498149/
Abstract

Ninety eight consecutive patients with an operative diagnosis of carcinoma of the head of the pancreas are discussed. Recent advances in the preoperative diagnosis and management appear to have failed to make a significant impact in non-specialised units, with 82 patients undergoing palliative procedures with an operative mortality of 25.6% rising to 36% when jaundice was present. Overall median survival was 202 days (range 35-967). Recurrence of jaundice developed in 42 patients and was more common with cholecysto-enteric bypass than in choledocho-enteric bypass. Forty four per cent of patients undergoing biliary bypass alone subsequently had signs of gastric outlet obstruction.

摘要

讨论了98例经手术诊断为胰头癌的连续患者。术前诊断和治疗的最新进展似乎未能在非专科单位产生重大影响,82例患者接受了姑息性手术,手术死亡率为25.6%,出现黄疸时升至36%。总体中位生存期为202天(范围35 - 967天)。42例患者出现黄疸复发,在胆囊肠吻合术比胆管肠吻合术中更常见。仅接受胆道旁路手术的患者中有44%随后出现胃出口梗阻的迹象。

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Palliation for carcinoma of head of pancreas.胰头癌的姑息治疗
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3
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Ann Surg. 1989 Oct;210(4):544-54; discussion 554-6. doi: 10.1097/00000658-198910000-00015.
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Pancreatic cancer in 1988. Possibilities and probabilities.1988年的胰腺癌。可能性与概率
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Surgical palliation for pancreatic carcinoma.胰腺癌的外科姑息治疗
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Surgical palliation for pancreatic cancer: will biliary bypass alone suffice?胰腺癌的手术姑息治疗:仅行胆道旁路术是否足够?
J R Soc Med. 1990 Jan;83(1):12-4. doi: 10.1177/014107689008300107.

本文引用的文献

1
POST-OPERATIVE RENAL FUNCTION IN OBSTRUCTIVE JAUNDICE: EFFECT OF A MANNITOL DIURESIS.梗阻性黄疸患者术后肾功能:甘露醇利尿的影响
Br Med J. 1965 Jan 9;1(5427):82-6. doi: 10.1136/bmj.1.5427.82.
2
The effect of preoperative bile salt administration on postoperative renal function in patients with obstructive jaundice.术前给予胆盐对梗阻性黄疸患者术后肾功能的影响。
Br J Surg. 1982 Dec;69(12):706-8. doi: 10.1002/bjs.1800691207.
3
Factors affecting mortality in biliary tract surgery.影响胆道手术死亡率的因素。
Am J Surg. 1981 Jan;141(1):66-72. doi: 10.1016/0002-9610(81)90014-3.
4
Ultrasonography, computed tomography, and cholescintigraphy in suspected obstructive jaundice--a prospective comparative study.超声检查、计算机断层扫描及胆管闪烁显像在疑似梗阻性黄疸中的应用——一项前瞻性对比研究
Gastroenterology. 1983 Jun;84(6):1492-7.
5
Prevention of postoperative renal failure in patients with obstructive jaundice--the role of bile salts.阻塞性黄疸患者术后肾衰竭的预防——胆盐的作用。
Br J Surg. 1983 Oct;70(10):590-5. doi: 10.1002/bjs.1800701008.
6
Should surgeons operate on the evidence of ultrasound alone in jaundiced patients?外科医生是否应该仅根据超声检查结果就对黄疸患者进行手术?
Br J Surg. 1983 Oct;70(10):587-9. doi: 10.1002/bjs.1800701007.
7
Surgical experience of deeply jaundiced patients with bile duct obstruction.胆管梗阻深度黄疸患者的手术经验
Br J Surg. 1984 Mar;71(3):234-8. doi: 10.1002/bjs.1800710326.
8
Surgical experience with pancreatic and periampullary cancer.胰腺和壶腹周围癌的手术经验。
Ann Surg. 1982 Mar;195(3):274-81. doi: 10.1097/00000658-198203000-00006.
9
Biliary bypass for ductal adenocarcinoma of the pancreas: Mayo Clinic experience, 1970-1975.胰腺导管腺癌的胆道搭桥术:梅奥诊所经验,1970 - 1975年
Mayo Clin Proc. 1980 Sep;55(9):537-40.
10
Gastric outlet obstruction after palliative surgery for cancer of head of pancreas.胰头癌姑息性手术后的胃出口梗阻
Arch Surg. 1983 May;118(5):550-3. doi: 10.1001/archsurg.1983.01390050034006.