新北欧饮食对腰围增大的成年人健康影响：一项 6 个月的随机对照试验。
Health effect of the New Nordic Diet in adults with increased waist circumference: a 6-mo randomized controlled trial.
机构信息
Department of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Frederiksberg C, Denmark (SKP, AD, AA, and TML); the NEXS, Faculty of Science, University of Copenhagen, København N, Denmark (ABJ and BK); the Department of Kinesiology, University of Waterloo, Waterloo, Canada (KDS); the Department of Clinical Biochemistry, Gentofte University Hospital, Hellerup, Denmark (SS); and the Institute of Preventive Medicine, Copenhagen University Hospitals, Frederiksberg Hospital, Frederiksberg, Denmark (CH).
出版信息
Am J Clin Nutr. 2014 Jan;99(1):35-45. doi: 10.3945/ajcn.113.069393. Epub 2013 Nov 20.
BACKGROUND
The regional Mediterranean Diet has been associated with lower risk of disease.
OBJECTIVE
We tested the health effects of the New Nordic Diet (NND), which is a gastronomically driven regional, organic, and environmentally friendly diet, in a carefully controlled but free-living setting.
DESIGN
A total of 181 centrally obese men and women, with a mean (range) age of 42 y (20-66 y), body mass index (in kg/m(2)) of 30.2 (22.6-47.3), and waist circumference of 100 cm (80-138 cm) were randomly assigned to receive either the NND (high in fruit, vegetables, whole grains, and fish) or an average Danish diet (ADD) for 26 wk. Participants received cookbooks and all foods ad libitum and free of charge by using a shop model. The primary endpoint was the weight change analyzed by both completer and intention-to-treat analyses.
RESULTS
A total of 147 subjects [81% (NND 81%; ADD 82%)] completed the intervention. A high dietary compliance was achieved, with significant differences in dietary intakes between groups. The mean (±SEM) weight change was -4.7 ± 0.5 kg for the NND compared with -1.5 ± 0.5 kg for the ADD (adjusted difference: -3.2 kg; 95% CI: -4.6, -1.8 kg; P < 0.001) for the completer analysis, and the difference was -3.0 kg (95% CI: -4.0, -2.1 kg) for the intention-to-treat analysis. The NND produced greater reductions in systolic blood pressure (adjusted difference: -5.1 mm Hg; 95% CI: -8.2, -2.1 mm Hg) and diastolic blood pressure (adjusted difference: -3.2 mm Hg; 95% CI: -5.7, -0.8 mm Hg) than did the ADD.
CONCLUSION
An ad libitum NND produces weight loss and blood pressure reduction in centrally obese individuals. This trial was registered at www.clinicaltrials.gov as NCT01195610.
背景
地中海饮食区域与较低的疾病风险相关。
目的
我们在精心控制但自由生活的环境中，测试了新北欧饮食（NND）的健康影响，NND 是一种以美食为导向的区域性、有机和环保饮食。
设计
总共 181 名中心性肥胖的男性和女性，平均（范围）年龄 42 岁（20-66 岁），体重指数（kg/m2）为 30.2（22.6-47.3），腰围 100cm（80-138cm），随机分为接受 NND（富含水果、蔬菜、全谷物和鱼类）或平均丹麦饮食（ADD）26 周。参与者通过使用商店模式接受食谱和所有食物自由食用和免费。主要终点是通过完成者和意向治疗分析分析的体重变化。
结果
共有 147 名受试者[81%（NND 81%；ADD 82%）]完成了干预。实现了高饮食依从性，两组之间的饮食摄入量存在显著差异。NND 的平均（±SEM）体重变化为-4.7±0.5kg，而 ADD 为-1.5±0.5kg（调整差异：-3.2kg；95%置信区间：-4.6，-1.8kg；P<0.001），对于完成者分析，差异为-3.0kg（95%置信区间：-4.0，-2.1kg），对于意向治疗分析。NND 可降低收缩压（调整差异：-5.1mmHg；95%置信区间：-8.2，-2.1mmHg）和舒张压（调整差异：-3.2mmHg；95%置信区间：-5.7，-0.8mmHg）的降幅大于 ADD。
结论
自由摄入 NND 可减轻中心性肥胖个体的体重和降低血压。本试验在 www.clinicaltrials.gov 注册为 NCT01195610。
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