Saraji Mohammad, Boroujeni Malihe Khalili
Department of Chemistry, Isfahan University of Technology, Isfahan, 84156-83111, Iran,
Anal Bioanal Chem. 2014 Mar;406(8):2027-66. doi: 10.1007/s00216-013-7467-z. Epub 2013 Nov 21.
During the past 7 years and since the introduction of dispersive liquid-liquid microextraction (DLLME), the method has gained widespread acceptance as a simple, fast, and miniaturized sample preparation technique. Owing to its simplicity of operation, rapidity, low cost, high recovery, and low consumption of organic solvents and reagents, it has been applied for determination of a vast variety of organic and inorganic compounds in different matrices. This review summarizes the DLLME principles, historical developments, and various modes of the technique, recent trends, and selected applications. The main focus is on recent technological advances and important applications of DLLME. In this review, six important aspects in the development of DLLME are discussed: (1) the type of extraction solvent, (2) the type of disperser solvent, (3) combination of DLLME with other extraction methods, (4) automation of DLLME, (5) derivatization reactions in DLLME, and (6) the application of DLLME for metal analysis. Literature published from 2010 to April 2013 is covered.
在过去7年以及自分散液液微萃取（DLLME）方法问世以来，该方法作为一种简单、快速且小型化的样品前处理技术已获得广泛认可。由于其操作简便、速度快、成本低、回收率高以及有机溶剂和试剂消耗少，它已被用于测定不同基质中各种各样的有机和无机化合物。本综述总结了DLLME的原理、历史发展、该技术的各种模式、近期趋势以及选定的应用。主要重点是DLLME的近期技术进展和重要应用。在本综述中，讨论了DLLME发展中的六个重要方面：（1）萃取溶剂的类型，（2）分散剂溶剂的类型，（3）DLLME与其他萃取方法的结合，（4）DLLME的自动化，（5）DLLME中的衍生化反应，以及（6）DLLME在金属分析中的应用。涵盖了2010年至2013年4月发表的文献。
