Group Health Research Institute, 1730 Minor Ave., Suite 1600, Seattle, 98101, WA, USA,
Curr Psychiatry Rep. 2013 Dec;15(12):426. doi: 10.1007/s11920-013-0426-8.
Recent reports of antipsychotic medication use in pediatric populations describe large increases in rates of use. Much interest in the increasing use has focused on potentially inappropriate prescribing for non-Food and Drug Administration-approved uses and use amongst youth with no mental health diagnosis. Different studies of antipsychotic use have used different time periods, geographic and insurance populations of youth, and aggregations of diagnoses. We review recent estimates of use and comment on the similarities and dissimilarities in rates of use. We also report new data obtained on 11 health maintenance organizations that are members of the Mental Health Research Network in order to update and extend the knowledge base on use by diagnostic indication. Results indicate that most use in pediatric populations is for disruptive behaviors and not psychotic disorders. Differences in estimates are likely a function of differences in methodology; however, there is remarkable consistency in estimates of use by diagnosis.
最近有报道称，儿童人群中使用抗精神病药物的情况有所增加。人们对这种使用量的增加非常关注，主要集中在未经食品和药物管理局批准的用途上的潜在不当处方，以及在没有精神健康诊断的年轻人中使用。不同的抗精神病药物使用研究使用了不同的时间段、地理和保险青年人群，以及诊断的聚合。我们回顾了最近的使用估计，并对使用率的相似性和差异性进行了评论。我们还报告了在 11 个健康维护组织中获得的新数据，这些组织是心理健康研究网络的成员，以便更新和扩展关于诊断指示的使用知识库。结果表明，大多数儿童人群的使用是为了治疗破坏性行为，而不是精神病。估计值的差异可能是由于方法学的差异造成的；然而，按诊断划分的使用估计值存在显著的一致性。
