Department of Radiology, University of Michigan, Health System, Taubman Center, Ann Arbor, Michigan.
Semin Respir Crit Care Med. 2013 Dec;34(6):738-47. doi: 10.1055/s-0033-1358615. Epub 2013 Nov 20.
Lung cancer screening with low dose computed tomography (CT) is the only method ever proven to reduce lung cancer-specific mortality in high-risk current and former cigarette smokers. Radiation exposure from annual screening CT examinations and subsequent CT and nuclear medicine testing to further evaluate positive screening CTs is sometimes raised as a reason to avoid screening and is often misunderstood. With all testing, there are potential benefits and risks. As we sit on the brink of widespread adoption of lung cancer screening CT, we aim to explain why the risks associated with radiation exposure from lung cancer screening are very low and should not be used to avoid screening or dissuade individuals who qualify for screening CT to participate in a lung cancer screening program.
低剂量计算机断层扫描（CT）肺癌筛查是唯一被证明能降低高危现吸烟者和曾吸烟者肺癌特异性死亡率的方法。由于年度筛查 CT 检查以及随后为进一步评估阳性筛查 CT 而进行的 CT 和核医学检查会带来辐射暴露，因此有人提出了避免筛查的理由，而且这种说法常常被误解。对于所有的检查，都存在潜在的益处和风险。鉴于我们即将广泛采用肺癌筛查 CT，我们旨在解释为什么与肺癌筛查相关的辐射暴露风险非常低，不应以此作为避免筛查的理由，也不应劝阻有资格接受筛查 CT 的人不参加肺癌筛查计划。
