Santelli Claudio, Schaeffter Tobias, Kozerke Sebastian
Imaging Sciences and Biomedical Engineering, King's College, London, United Kingdom; Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.
Magn Reson Med. 2014 Nov;72(5):1233-45. doi: 10.1002/mrm.25030. Epub 2013 Nov 20.
To extend SPIRiT to additionally exploit temporal correlations for highly accelerated generalized phase-contrast MRI and to compare the performance of the proposed radial k-t SPIRiT method relative to frame-by-frame SPIRiT and radial k-t GRAPPA reconstruction for velocity and turbulence mapping in the aortic arch.
Free-breathing navigator-gated two-dimensional radial cine imaging with three-directional multi-point velocity encoding was implemented and fully sampled data were obtained in the aortic arch of healthy volunteers. Velocities were encoded with three different first gradient moments per axis to permit quantification of mean velocity and turbulent kinetic energy. Velocity and turbulent kinetic energy maps from up to 14-fold undersampled data were compared for k-t SPIRiT, frame-by-frame SPIRiT, and k-t GRAPPA relative to the fully sampled reference.
Using k-t SPIRiT, improvements in magnitude and velocity reconstruction accuracy were found. Temporally resolved magnitude profiles revealed a reduction in spatial blurring with k-t SPIRiT compared with frame-by-frame SPIRiT and k-t GRAPPA for all velocity encodings, leading to improved estimates of turbulent kinetic energy.
k-t SPIRiT offers improved reconstruction accuracy at high radial undersampling factors and hence facilitates the use of generalized phase-contrast MRI for routine use.
扩展自并行图像重建技术(SPIRiT)以额外利用时间相关性,用于高度加速的广义相位对比磁共振成像(MRI),并比较所提出的径向k-t SPIRiT方法相对于逐帧SPIRiT以及径向k-t广义自校准部分并行采集(GRAPPA)重建在主动脉弓速度和湍流映射方面的性能。
实施自由呼吸导航门控二维径向电影成像,采用三向多点速度编码,在健康志愿者的主动脉弓中获取完全采样数据。每个轴用三个不同的第一梯度矩对速度进行编码,以实现平均速度和湍流动能的量化。将来自高达14倍欠采样数据的速度和湍流动能图,针对k-t SPIRiT、逐帧SPIRiT和k-t GRAPPA与完全采样参考进行比较。
使用k-t SPIRiT时,发现幅度和速度重建精度有所提高。对于所有速度编码,与逐帧SPIRiT和k-t GRAPPA相比,时间分辨幅度剖面显示k-t SPIRiT的空间模糊减少,从而改善了湍流动能的估计。
k-t SPIRiT在高径向欠采样因子下提供了更高的重建精度,因此便于将广义相位对比MRI用于常规应用。