Department of Pharmaceutical Sciences, University of Antwerpen (U.I.A.), Universiteitsplein 1, B-2610, Wilrijk, Belgium.
Biol Trace Elem Res. 1983 Apr;5(2):103-13. doi: 10.1007/BF02916630.
The selenium state of 40 elderly Belgian people, residing in geriatric homes, has been evaluated. Data are presented on the selenium (Se) contents of their blood, plasma, and erythrocytes. The activity of glutathione peroxidase (GSH-Px) has been assayed. All data were compared with those obtained for 164 young, working adults as presented in Part I of this study. Plasma selenium levels were significantly lower in the old (73 ng/mL) as compared to the young people (97 ng/mL), but erythrocyte Se levels (200 ng/mL) and GSH-Px activity were significantly higher.The selenium concentration in plasma during infancy has also been estimated. The results reveal a very low Se level during the first months of life, with a gradual increase with age. The results are discussed in the light of literature data.
对 40 名居住在养老院的比利时老年人的硒状态进行了评估。报告了他们血液、血浆和红细胞中的硒(Se)含量。还测定了谷胱甘肽过氧化物酶(GSH-Px)的活性。所有数据均与本研究第一部分中 164 名年轻成年工人的结果进行了比较。老年人的血浆硒水平(73ng/ml)明显低于年轻人(97ng/ml),但红细胞 Se 水平(200ng/ml)和 GSH-Px 活性明显更高。还估算了婴儿期血浆中的硒浓度。结果显示,生命的最初几个月中硒水平非常低,随着年龄的增长逐渐增加。结果结合文献数据进行了讨论。