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基于扩散距离和 BLDA 的颅内 EEG 自动癫痫发作检测。

Automatic seizure detection using diffusion distance and BLDA in intracranial EEG.

机构信息

School of Information Science and Engineering, Shandong University, PR China.

School of Information Science and Engineering, Shandong University, PR China.

出版信息

Epilepsy Behav. 2014 Feb;31:339-45. doi: 10.1016/j.yebeh.2013.10.005. Epub 2013 Nov 20.

DOI:10.1016/j.yebeh.2013.10.005
PMID:24269028
Abstract

Approximately 1% of the world's population suffers from epilepsy. An automatic seizure detection system is of great significance in the monitoring and diagnosis of epilepsy. In this paper, a novel method is proposed for automatic seizure detection in intracranial EEG recordings. The EEG recordings are divided into 4-s epochs, and then wavelet decomposition with five scales is performed to the EEG epochs. Detail signals at scales 3, 4, and 5 are selected to form a signal distribution. The diffusion distances are extracted as features, and Bayesian linear discriminant analysis (BLDA) is used as the classifier. A total of 193.75h of intracranial EEG recordings from 21 patients having 87 seizures are employed to evaluate the system, and the average sensitivity of 94.99%, specificity of 98.74%, and false-detection rate of 0.24/h are achieved. The seizure detection system based on diffusion distance yields a high sensitivity as well as a low false-detection rate for long-term EEG recordings.

摘要

大约有 1%的世界人口患有癫痫。自动癫痫检测系统对于癫痫的监测和诊断具有重要意义。本文提出了一种新的方法,用于颅内 EEG 记录中的自动癫痫检测。将 EEG 记录分成 4 秒的时间段,然后对 EEG 时间段进行五尺度的小波分解。选择尺度 3、4 和 5 的细节信号来形成信号分布。提取扩散距离作为特征,并使用贝叶斯线性判别分析 (BLDA) 作为分类器。该系统共使用了 21 名患者的 193.75 小时颅内 EEG 记录,记录了 87 次发作,平均灵敏度为 94.99%,特异性为 98.74%,假阳性率为 0.24/h。基于扩散距离的癫痫检测系统在长时间 EEG 记录中具有较高的灵敏度和较低的假阳性率。

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