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由气单胞菌属引起的肝硬化患者严重脓毒症。

Severe sepsis due to Aeromonas aquariorum in a patient with liver cirrhosis.

机构信息

Bio-Safety Research Institute and College of Veterinary Medicine, Chonbuk National University.

出版信息

Jpn J Infect Dis. 2013;66(6):519-22. doi: 10.7883/yoken.66.519.

Abstract

Thus far, Aeromonas aquariorum infection has been unrecorded in Korea. Herein, we report a fatal case of A. aquariorum infection in a 77-year-old male patient with liver cirrhosis. The bacterium isolated from a blood culture was initially mistaken as Aeromonas hydrophila using the Vitek2 identification system. In spite of intravenous ceftriaxone therapy, the patient was exacerbated by multiple organ dysfunction. By 4 days after admission, there was no hope for treatment or remission of symptoms and the patient was discharged. In the detailed microbiological investigations, the bacterium was identified as A. aquariorum harboring the act and alt genes, which encode cytotoxic and cytotonic enterotoxins.

摘要

迄今为止,韩国尚未记录到 Aquarium 气单胞菌感染。在此,我们报告了一例 77 岁男性肝硬化患者的致命 Aeromonas aquariorum 感染病例。从血培养中分离出的细菌最初被 Vitek2 鉴定系统误诊为嗜水气单胞菌。尽管静脉注射头孢曲松治疗,但该患者仍因多器官功能障碍而恶化。入院后 4 天,患者已无治疗或缓解症状的希望,遂出院。在详细的微生物学研究中,该细菌被鉴定为携带 act 和 alt 基因的 Aquarium 气单胞菌,这些基因编码细胞毒性和细胞毒性肠毒素。

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