Serviço de Hematologia, Universidade Federal do Triângulo Mineiro, UberabaMG.
Rev Soc Bras Med Trop. 2013 Sep-Oct;46(5):660-2. doi: 10.1590/0037-8682-0117-2013.
Saprophytic fungi are being increasingly recognized as etiologic agents of mycoses in immunosuppressed patients. We report a case of subcutaneous infiltration by Aureobasidium pullulans, likely due to traumatic inoculation, in a neutropenic patient during chemotherapy for chronic lymphocytic leukemia. The patient was treated with amphotericin B deoxycholate but was subsequently switched to itraconazole, which improved the lesion. This case highlights the importance of considering unusual fungal infections in critically ill patients such as those who are immunosuppressed due to chemotherapy. Diagnostic techniques and effective antifungal therapy have improved the prognosis of these cases.
腐生性真菌正日益被认为是免疫抑制患者真菌感染的病原体。我们报告了一例慢性淋巴细胞白血病化疗期间中性粒细胞减少症患者因创伤接种而发生的粘帚霉皮下浸润。患者接受两性霉素 B 脱氧胆酸盐治疗，但随后改用伊曲康唑，病变改善。该病例强调了在危重病患者（如因化疗而免疫抑制的患者）中考虑不常见真菌感染的重要性。诊断技术和有效的抗真菌治疗改善了这些病例的预后。
