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金合欢素——一种植物生长调节剂。

Castanospermine-a plant growth regulator.

机构信息

USDA-ARS, Western Regional Research Center, 800 Buchanan Street, 94710, Albany, California.

出版信息

J Chem Ecol. 1988 Jun;14(6):1467-73. doi: 10.1007/BF01012418.

DOI:10.1007/BF01012418
PMID:24276397
Abstract

Castanospermine, 1,6,7,8-tetrahydroxyoctahydroindolizine, has been shown to be a potent dicot phytotoxin. The effective concentration to inhibit root length elongation of dicot roots by 50% is 300 ppb, while the effective concentration against monocot roots is 200 ppm, i.e., 10(3) times less effective. In contrast swainsonine, 1,2,8-trihydroxyoctahydroindolizidine, is ineffective as an inhibitor of root length elongation.

摘要

金合欢素,1,6,7,8-四羟基辛氢吲哚嗪,已被证明是一种有效的双子叶植物毒素。抑制双子叶植物根伸长 50%的有效浓度为 300 ppb,而对单子叶植物根的有效浓度为 200 ppm,即效力降低 10(3)倍。相比之下,苦马豆素,1,2,8-三羟基辛氢吲哚嗪,作为根伸长抑制剂是无效的。

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1
Castanospermine-a plant growth regulator.金合欢素——一种植物生长调节剂。
J Chem Ecol. 1988 Jun;14(6):1467-73. doi: 10.1007/BF01012418.
2
The lesions of locoweed (Astragalus mollissimus), swainsonine, and castanospermine in rats.疯草(软毛黄芪)、苦马豆素和 castanospermine 对大鼠的损伤
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3
Studies on the mechanism of castanospermine inhibition of alpha- and beta-glucosidases.栗精胺对α-和β-葡萄糖苷酶抑制机制的研究。
Arch Biochem Biophys. 1984 May 1;230(2):668-75. doi: 10.1016/0003-9861(84)90448-x.
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Castanospermine, a tetrahydroxylated alkaloid that inhibits beta-glucosidase and beta-glucocerebrosidase.澳洲栗精胺,一种抑制β-葡萄糖苷酶和β-葡萄糖脑苷脂酶的四羟基化生物碱。
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The comparative pathology of the glycosidase inhibitors swainsonine, castanospermine, and calystegines A3, B2, and C1 in mice.糖苷酶抑制剂苦马豆素、栗精胺以及旋花茄胺A3、B2和C1在小鼠中的比较病理学
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Castanospermine vs. its 6-O-butanoyl analog: a comparison of toxicity and antiviral activity in vitro and in vivo.栗精胺与其6-O-丁酰基类似物的比较:体内外毒性及抗病毒活性对比
J Acquir Immune Defic Syndr (1988). 1991;4(1):48-55.
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Castanospermine inhibits the processing of the oligosaccharide portion of the influenza viral hemagglutinin.栗精胺抑制流感病毒血凝素寡糖部分的加工过程。
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Swainsonine and castanospermine blockade of mannose glycoprotein uptake by macrophages. Apparent inhibition of receptor-mediated endocytosis by endogenous ligands.
J Biol Chem. 1984 Dec 10;259(23):14637-41.
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本文引用的文献

1
Feeding deterrency of some pyrrolizidine, indolizidine, and quinolizidine alkaloids towards pea aphid (Acyrthosiphon pisum) and evidence for phloem transport of indolizidine alkaloid swainsonine.某些吡咯里西啶、吲哚里西啶和喹喏里西啶生物碱对豌豆蚜(Acyrthosiphon pisum)的拒食作用及吲哚里西啶生物碱苦马豆素韧皮部运输的证据。
J Chem Ecol. 1985 Aug;11(8):1045-51. doi: 10.1007/BF01020674.
2
Allelopathic polyacetylenes fromCentaurea repens (Russian knapweed).意大利苍耳中的化感多炔类物质。
J Chem Ecol. 1986 Jun;12(6):1205-11. doi: 10.1007/BF01012342.
3
Differential inhibition by castanospermine of various insect disaccharidases.
基于生态限制因子模型的植物化感激素兴奋效应的数学建模。
Dose Response. 2010 May 28;9(1):117-29. doi: 10.2203/dose-response.09-050.Liu.
4
Mathematical Modeling of Allelopathy. III. A Model for Curve-Fitting Allelochemical Dose Responses.化感作用的数学建模。III. 化感物质剂量反应曲线拟合模型。
Nonlinearity Biol Toxicol Med. 2003 Jan;1(1):37-50. doi: 10.1080/15401420390844456.
金雀花碱对各种昆虫二糖酶的差异抑制作用。
J Chem Ecol. 1987 Jul;13(7):1759-70. doi: 10.1007/BF00980216.
4
Mechanism of Inhibition of Jack Bean alpha-Mannosidase by Swainsonine.金雀花堿抑制刀豆α-甘露糖苷酶的机制。
Plant Physiol. 1983 Mar;71(3):551-4. doi: 10.1104/pp.71.3.551.
5
The Structure of Plant Cell Walls: VI. A Survey of the Walls of Suspension-cultured Monocots.植物细胞壁的结构:VI. 悬浮培养单子叶植物细胞壁综述
Plant Physiol. 1974 Jul;54(1):109-15. doi: 10.1104/pp.54.1.109.
6
Relation of glycosidases to bean hypocotyl growth.糖苷酶与豆芽下胚轴生长的关系。
Plant Physiol. 1970 Sep;46(3):458-62. doi: 10.1104/pp.46.3.458.
7
Loco intoxication: indolizidine alkaloids of spotted locoweed (Astragalus lentiginosus).局部中毒:斑点疯草(黄芪属扁豆状黄芪)中的吲哚里西啶生物碱。
Science. 1982 Apr 9;216(4542):190-1. doi: 10.1126/science.6801763.
8
Castanospermine inhibits the processing of the oligosaccharide portion of the influenza viral hemagglutinin.栗精胺抑制流感病毒血凝素寡糖部分的加工过程。
Biochemistry. 1983 Aug 2;22(16):3975-84. doi: 10.1021/bi00285a038.
9
Inhibition of processing of plant N-linked oligosaccharides by castanospermine.栗精胺对植物N-连接寡糖加工过程的抑制作用。
Arch Biochem Biophys. 1984 Feb 1;228(2):525-33. doi: 10.1016/0003-9861(84)90019-5.
10
Castanospermine, a tetrahydroxylated alkaloid that inhibits beta-glucosidase and beta-glucocerebrosidase.澳洲栗精胺,一种抑制β-葡萄糖苷酶和β-葡萄糖脑苷脂酶的四羟基化生物碱。
Arch Biochem Biophys. 1983 Mar;221(2):593-7. doi: 10.1016/0003-9861(83)90181-9.