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电针对胰腺癌疼痛的治疗:一项随机对照试验。

Electroacupuncture treatment for pancreatic cancer pain: a randomized controlled trial.

机构信息

Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.

出版信息

Pancreatology. 2013 Nov-Dec;13(6):594-7. doi: 10.1016/j.pan.2013.10.007. Epub 2013 Oct 23.

DOI:10.1016/j.pan.2013.10.007
PMID:24280575
Abstract

BACKGROUND

Pancreatic cancer is often accompanied by severe abdominal or back pain. It's the first study to evaluate the analgesic effect of electroacupuncture on pancreatic cancer pain. A randomized controlled trial compared electroacupuncture with control acupuncture using the placebo needle.

METHODS

Sixty patients with pancreatic cancer pain were randomly assigned to the electroacupuncture group (n = 30) and the placebo control group (n = 30). Patients were treated on Jiaji (Ex-B2) points T8-T12 bilaterally for 30 min once a day for 3 days. Pain intensity was assessed with numerical rated scales (NRS) before the treatment (Baseline), after 3 treatments, and 2 days follow-up.

RESULTS

Baseline characteristics were similar in the two groups. After 3 treatment, pain intensity on NRS decreased compared with Baseline (-1.67, 95% confidence interval [CI] -1.46 to -1.87) in the electroacupuncture group; there was little change (-0.13, 95% CI 0.08 to -0.35) in control group; the difference between two groups was statistically significant (P < 0.001). Follow-up also found a significant reduction in pain intensity in the electroacupuncture group compared with the control group (P < 0.001).

CONCLUSIONS

Electroacupuncture was an effective treatment for relieving pancreatic cancer pain.

摘要

背景

胰腺癌常伴有严重的腹痛或背痛。这是第一项评估电针对胰腺癌疼痛的镇痛效果的随机对照试验。该试验将电针与使用安慰剂针的对照针刺进行了比较。

方法

将 60 例胰腺癌疼痛患者随机分为电针组(n=30)和安慰剂对照组(n=30)。患者每天在双侧 T8-T12 夹脊穴接受 30 分钟的治疗,共治疗 3 天。在治疗前(基线)、治疗后 3 次和治疗后 2 天,使用数字评分量表(NRS)评估疼痛强度。

结果

两组的基线特征相似。与基线相比,电针组的 NRS 疼痛强度在治疗 3 次后降低(-1.67,95%置信区间[CI] -1.46 至-1.87);对照组的变化很小(-0.13,95% CI 0.08 至-0.35);两组之间的差异具有统计学意义(P<0.001)。随访时还发现电针组的疼痛强度与对照组相比显著降低(P<0.001)。

结论

电针对缓解胰腺癌疼痛是一种有效的治疗方法。

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