Alvarado-Cabrero Isabel, Rodríguez-Gómez Adriana, Castelan-Pedraza Jorge, Valencia-Cedillo Raquel
Department of Pathology, Mexican Oncology Hospital, Mexico, D.F., Mexico.
Anal Quant Cytopathol Histpathol. 2013 Oct;35(5):241-8.
To determine the frequency of metastatic ovarian tumors and to identify their clinicopathologic features.
A total of 150 patients with pathologically confirmed metastatic ovarian carcinoma who were treated between 1995 and 2011 at the Mexican Oncology Hospital were identified by retrospective review. Clinicopathologic data were analyzed.
Metastatic ovarian carcinoma accounted for 15.7% of all ovarian malignancies. The primary sites of nongynecologic tumors were the colon (30%), stomach (16%), appendix (13%), breast (13%), pancreas (12%), biliary tract (15%), and liver (4%). Gynecologic primary sites were the uterine cervix (4%) and the uterine body (23%). Primary malignancies were detected first in 66 patients (44%) and simultaneously with ovarian metastasis in 53 patients (35.3%). An ovarian mass was the first manifestation of disease in 20.6% of the cases. The patients ranged in age from 26 to 72 years (mean, 51). Krukenberg tumors were found in 35 patients (23%). The cut surfaces of the ovaries were solid in 68 patients, solid-cystic in 38, and multicystic in 44.
Metastatic ovarian carcinomas are an important group of ovarian neoplasms, constituting 15.7% of all ovarian malignancies. Most of them arise from the gastrointestinal tract.
确定转移性卵巢肿瘤的发生率并识别其临床病理特征。
通过回顾性研究，确定了1995年至2011年期间在墨西哥肿瘤医院接受治疗的150例经病理证实的转移性卵巢癌患者。对临床病理数据进行了分析。
转移性卵巢癌占所有卵巢恶性肿瘤的15.7%。非妇科肿瘤的原发部位为结肠（30%）、胃（16%）、阑尾（13%）、乳腺（13%）、胰腺（12%）、胆道（15%）和肝脏（4%）。妇科原发部位为子宫颈（4%）和子宫体（23%）。66例患者（44%）首先检测到原发性恶性肿瘤，53例患者（35.3%）同时发现卵巢转移。20.6%的病例中卵巢肿块是疾病的首发表现。患者年龄在26至72岁之间（平均51岁）。35例患者（23%）发现克鲁肯伯格瘤。卵巢切面68例为实性，38例为实性-囊性，44例为多囊性。
转移性卵巢癌是卵巢肿瘤的一个重要群体，占所有卵巢恶性肿瘤的15.7%。其中大多数起源于胃肠道。
