Catalano Leonardo N, Villar Diaz Michelle, Vázquez Guzmán Miguel, Negron Ivette, Rivera Rosa Edgardo
Department of Obstetrics and Gynecology, San Juan City Hospital, San Juan, Puerto Rico.
Bol Asoc Med P R. 2013;105(3):13-6.
evaluation of Nifedipine protocol success defined as postponement of labor for 48 hours.
evaluation of the presence of risk factors in patients that develop preterm labor and delivery outcome.
Chart review retrospective study with patients admitted to the Hospital of the Metropolitan Area of San Juan in the period of January 1,2009 to December 31, 2010 with diagnosis of preterm labor. A total of 382 patient's records were evaluated for inclusion and exclusion criteria. 48 met all the requirements to be included in the study.
There were 68.8% patients who successfully completed the 48 hours postponement of labor required to administer corticosteroid therapy for fetal lung maturation. Risk factors for preterm labor commonly observed in the study group were urinary tract infection (60.4%), previous preterm labor (43.8%), multiple gestations (12.5%), and preterm premature rupture of membranes (10.4%).
The use of Nifedipine therapy in patients with preterm labor between 24-34 weeks of gestational age can be effective in the postponement of labor for 48 hours so that the patient can receive corticosteroid fetal lung maturation therapy. The most common risk factor observed in this group of patients with preterm labor was urinary tract infection.
评估硝苯地平方案的成功率，定义为将分娩推迟48小时。
评估发生早产的患者中危险因素的存在情况以及分娩结局。
对2009年1月1日至2010年12月31日期间入住圣胡安都会区医院且诊断为早产的患者进行回顾性图表研究。共评估了382例患者的病历以确定纳入和排除标准。48例符合纳入该研究的所有要求。
68.8%的患者成功完成了为促进胎儿肺成熟而进行的48小时分娩推迟，以便进行皮质类固醇治疗。研究组中常见的早产危险因素为尿路感染（60.4%）、既往早产（43.8%）、多胎妊娠（12.5%）和胎膜早破（10.4%）。
在孕24 - 34周的早产患者中使用硝苯地平治疗可有效将分娩推迟48小时，从而使患者能够接受皮质类固醇胎儿肺成熟治疗。在这组早产患者中观察到的最常见危险因素是尿路感染。
