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[B族链球菌作为人类新生儿感染的病因:流行病学、发病机制、临床特征、治疗与预防]

[Group B streptococci as a cause of neonatal infections in humans: epidemiology, pathogenesis, clinical features, treatment and prophylaxis].

作者信息

Decheva A

出版信息

Akush Ginekol (Sofiia). 2013;52(3):55-60.

PMID:24283065
Abstract

This paper aims to draw the attention of Bulgarian gynecologists, pediatricians, microbiologists on group B streptococci as a cause of serious invasive neonatal diseases associated with high mortality rate or disability. Epidemiology, pathogenesis and clinical features of the infection are described. Data on the antibiotic susceptibility and recommendations for treatment are presented. The main purpose of the paper is to lay particular stress on the importance of intrapartum antibiotic prophylaxis for pregnant women who are positive for rectovaginal group B streptococcal colonization. This measure was introduced in the USA (guidelines from 1996, 2002, 2010 years), it proved its efficacy and now a lot of the European countries put efforts to adopt it in their health-care system.

摘要

本文旨在引起保加利亚妇科医生、儿科医生、微生物学家对B族链球菌的关注,其是导致严重侵袭性新生儿疾病的原因,这些疾病伴有高死亡率或致残率。文中描述了该感染的流行病学、发病机制及临床特征。还介绍了抗生素敏感性数据及治疗建议。本文的主要目的是特别强调对直肠阴道B族链球菌定植呈阳性的孕妇进行产时抗生素预防的重要性。这一措施已在美国推行(1996年、2002年、2010年的指南),并已证明其有效性,现在许多欧洲国家正努力在其医疗体系中采用这一措施。

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