Le Gall E, Picaud J C, Treguier C, Fiant M, Oger M O, Jézéquel C
Arch Fr Pediatr. 1986 Mar;43(3):191-3.
We report 2 cases of neonatal auto-immune thrombocytopenia treated with high-dose intravenous gamma-globulins. Efficacy of treatment was immediate, inducing an increase in platelet levels which was transitory during the first 2 weeks but stabilized in the third week. Tolerance was excellent. Injections of 400 mg/kg/day repeated for 4 to 5 days should be preferred to a single dose of 1 to 2 g/kg.
我们报告了2例接受大剂量静脉注射丙种球蛋白治疗的新生儿自身免疫性血小板减少症病例。治疗效果立竿见影,血小板水平升高,在最初2周内是暂时的,但在第3周稳定下来。耐受性良好。与单次剂量1至2 g/kg相比,更宜采用400 mg/kg/天的剂量重复注射4至5天。