• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Investigation of an interleukin-6 receptor gene polymorphism (rs2228145) as a predictor of cardiovascular mortality in inflammatory polyarthritis: results from the Norfolk Arthritis Register.

作者信息

Ibrahim Ibrahim, McAllister Kate, Plant Darren, Symmons Deborah, Marshall Tarnya, Barton Anne, Eyre Stephen

机构信息

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, University of Manchester, , Manchester, UK.

出版信息

Ann Rheum Dis. 2014 Apr;73(4):787-8. doi: 10.1136/annrheumdis-2013-204330. Epub 2013 Nov 27.

DOI:10.1136/annrheumdis-2013-204330
PMID:24285489
Abstract
摘要

相似文献

1
Investigation of an interleukin-6 receptor gene polymorphism (rs2228145) as a predictor of cardiovascular mortality in inflammatory polyarthritis: results from the Norfolk Arthritis Register.白细胞介素-6受体基因多态性（rs2228145）作为炎症性多关节炎心血管死亡率预测指标的研究：来自诺福克关节炎登记处的结果
Ann Rheum Dis. 2014 Apr;73(4):787-8. doi: 10.1136/annrheumdis-2013-204330. Epub 2013 Nov 27.
2
Investigation of C reactive protein gene polymorphisms as predictors of cardiovascular mortality in inflammatory polyarthritis: results from the Norfolk Arthritis Register.炎症性多关节炎中C反应蛋白基因多态性作为心血管死亡率预测指标的研究：来自诺福克关节炎登记处的结果
Ann Rheum Dis. 2013 Aug;72(8):1429-30. doi: 10.1136/annrheumdis-2012-202920. Epub 2013 Apr 18.
3
Interleukin 6 Receptor (IL6-R) Gene Polymorphisms Underlie Susceptibility to Rheumatoid Arthritis.白细胞介素6受体（IL6-R）基因多态性是类风湿关节炎易感性的基础。
Clin Lab. 2017 Sep 1;63(9):1365-1369. doi: 10.7754/Clin.Lab.2017.170216.
4
Association of chemokine CXC ligand 12 gene polymorphism (rs1746048) with cardiovascular mortality in patients with rheumatoid arthritis: results from the Norfolk Arthritis Register.趋化因子CXC配体12基因多态性（rs1746048）与类风湿性关节炎患者心血管死亡率的关联：来自诺福克关节炎登记处的结果
Ann Rheum Dis. 2015 Nov;74(11):2099-102. doi: 10.1136/annrheumdis-2015-207851. Epub 2015 Aug 31.
5
Interleukin-6-receptor polymorphisms rs12083537, rs2228145, and rs4329505 as predictors of response to tocilizumab in rheumatoid arthritis.白细胞介素-6 受体多态性 rs12083537、rs2228145 和 rs4329505 作为类风湿关节炎患者对托珠单抗治疗反应的预测因子。
Pharmacogenet Genomics. 2014 Aug;24(8):401-5. doi: 10.1097/FPC.0000000000000071.
6
Early inflammatory polyarthritis: results from the norfolk arthritis register with a review of the literature. I. Risk factors for the development of inflammatory polyarthritis and rheumatoid arthritis.早期炎症性多关节炎：诺福克关节炎登记处的结果及文献综述。I. 炎症性多关节炎和类风湿关节炎发生的危险因素。
Rheumatology (Oxford). 2000 Aug;39(8):835-43. doi: 10.1093/rheumatology/39.8.835.
7
Lack of association of IL6R rs2228145 and IL6ST/gp130 rs2228044 gene polymorphisms with cardiovascular disease in patients with rheumatoid arthritis.类风湿关节炎患者中IL6R rs2228145和IL6ST/gp130 rs2228044基因多态性与心血管疾病无关联。
Tissue Antigens. 2011 Dec;78(6):438-41. doi: 10.1111/j.1399-0039.2011.01774.x. Epub 2011 Oct 10.
8
The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.类风湿关节炎遗传易感性标志物在预测早期炎症性多关节炎患者侵蚀性疾病中的作用：来自诺福克关节炎登记处的结果。
Rheumatology (Oxford). 2011 Jan;50(1):78-84. doi: 10.1093/rheumatology/keq032. Epub 2010 Mar 10.
9
Combined effect of C-reactive protein gene SNP +2147 A/G and interleukin-6 receptor gene SNP rs2229238 C/T on anthropometric characteristics among school children in Taiwan.C 反应蛋白基因 SNP+2147A/G 与白细胞介素-6 受体基因 SNP rs2229238C/T 联合对台湾地区学龄儿童人体测量特征的影响。
Int J Obes (Lond). 2011 Apr;35(4):587-94. doi: 10.1038/ijo.2010.195. Epub 2010 Sep 21.
10
Influence of IL6R rs8192284 polymorphism status in disease activity in rheumatoid arthritis.白细胞介素 6 受体 rs8192284 多态性对类风湿关节炎疾病活动的影响。
J Rheumatol. 2010 Aug 1;37(8):1579-81. doi: 10.3899/jrheum.091455. Epub 2010 Jun 15.

引用本文的文献

1
Relationship Between Interleukin-6 -174G/C Genetic Variant and Efficacy of Methotrexate Treatment in Psoriatic Arthritis Patients.白细胞介素-6 -174G/C基因变异与甲氨蝶呤治疗银屑病关节炎患者疗效的关系
Pharmgenomics Pers Med. 2021 Jan 28;14:157-166. doi: 10.2147/PGPM.S264555. eCollection 2021.
2
Sudden cardiac death in patients with rheumatoid arthritis.类风湿关节炎患者的心脏性猝死
World J Cardiol. 2017 Jul 26;9(7):562-573. doi: 10.4330/wjc.v9.i7.562.
3
The rs2228145 polymorphism in the interleukin-6 receptor and its association with long-term prognosis after myocardial infarction in a pilot study.
白细胞介素-6受体基因rs2228145多态性及其与心肌梗死后长期预后的相关性：一项初步研究
Arch Med Sci. 2017 Feb 1;13(1):93-99. doi: 10.5114/aoms.2016.58636. Epub 2016 Mar 17.
4
Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.HLA-DRB1单倍型与类风湿关节炎严重程度、死亡率及治疗反应的关联
JAMA. 2015 Apr 28;313(16):1645-56. doi: 10.1001/jama.2015.3435.