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从饮用水中分离出的耐碳青霉烯类菌株丰蒂氏沙雷氏菌UTAD54的基因组序列草图

Draft Genome Sequence of Serratia fonticola UTAD54, a Carbapenem-Resistant Strain Isolated from Drinking Water.

作者信息

Henriques Isabel, Jucá Ramos Rommel Thiago, Baraúna Rafael Azevedo, de Sá Pablo Henrique, Marinho Almeida Diogo, Carneiro Adriana Ribeiro, Barbosa Silvanira, Pereira Anabela, Alves Artur, Saavedra Maria José, Egas Conceição, Silva Artur, Correia António

机构信息

Department of Biology and CESAM, University of Aveiro, Campus Universitário de Santiago, Aveiro, Portugal.

出版信息

Genome Announc. 2013 Nov 27;1(6):e00970-13. doi: 10.1128/genomeA.00970-13.

DOI:10.1128/genomeA.00970-13
PMID:24285645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3869330/
Abstract

Serratia fonticola UTAD54 is an environmental isolate that is resistant to carbapenems due to the presence of a class A carbapenemase and a metallo-β-lactamase that are unique to this strain. Its draft genome sequence was obtained to clarify the molecular basis of its carbapenem resistance and identify the genomic context of its carbapenem resistance determinants.

摘要

弗氏沙雷氏菌UTAD54是一种环境分离株，由于存在该菌株特有的A类碳青霉烯酶和金属β-内酰胺酶，对碳青霉烯类耐药。获取了其基因组草图序列，以阐明其碳青霉烯耐药性的分子基础，并确定其碳青霉烯耐药决定因素的基因组背景。

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Microb Biotechnol. 2013 Mar;6(2):150-6. doi: 10.1111/1751-7915.12006. Epub 2012 Dec 2.
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J Am Chem Soc. 2012 Nov 7;134(44):18275-85. doi: 10.1021/ja304460j. Epub 2012 Oct 29.
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Serratia infections: from military experiments to current practice.沙雷氏菌感染：从军事实验到当前实践。
Clin Microbiol Rev. 2011 Oct;24(4):755-91. doi: 10.1128/CMR.00017-11.
4
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Antimicrob Agents Chemother. 2011 Nov;55(11):5392-5. doi: 10.1128/AAC.00429-11. Epub 2011 Aug 29.
5
Crystal structure of Serratia fonticola Sfh-I: activation of the nucleophile in mono-zinc metallo-β-lactamases.希瓦氏菌属 Sfh-I 晶体结构：单锌金属β-内酰胺酶中亲核试剂的活化。
J Mol Biol. 2011 Sep 2;411(5):951-9. doi: 10.1016/j.jmb.2011.06.043. Epub 2011 Jul 6.
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