Sporea Ioan, Gilja Odd Helge, Bota Simona, Şirli Roxana, Popescu Alina
Department of Gastroenterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy Timisoara, Romania; E-mail:
Med Ultrason. 2013 Dec;15(4):304-14. doi: 10.11152/mu.2013.2066.154.isp23.
Liver fibrosis evaluation is very important for treatment and prognosis in patients with chronic liver disease. The "gold-standard" method for liver fibrosis assessment is still considered to be the liver biopsy, but in the last years non-invasive methods have increasingly been used, especially ultrasound based elastographic ones. The oldest and the only validated elastographic method for non-invasive liver fibrosis evaluation is Transient Elastography (TE). In the last 2-3 years, similar results to TE for liver fibrosis assessment were obtained by using Acoustic Radiation Force Impulse (ARFI) Elastography. More recently, Real Time Shear Wave Elastography (SWE) was developed and promising results were obtained by this technique. Strain elastography is less used in clinical practice for non-invasive liver fibrosis assessment. TE is also useful for predicting liver cirrhosis complications, especially portal hypertension. ARFI elastography seems to be inferior to TE in this field.
肝纤维化评估对于慢性肝病患者的治疗和预后非常重要。肝纤维化评估的“金标准”方法仍被认为是肝活检，但近年来，非侵入性方法的使用越来越多，尤其是基于超声的弹性成像方法。用于非侵入性肝纤维化评估的最古老且唯一经过验证的弹性成像方法是瞬时弹性成像（TE）。在过去的两到三年中，使用声辐射力脉冲（ARFI）弹性成像获得了与TE用于肝纤维化评估相似的结果。最近，实时剪切波弹性成像（SWE）得到了发展，并且该技术取得了有前景的结果。应变弹性成像在临床实践中较少用于非侵入性肝纤维化评估。TE对于预测肝硬化并发症，尤其是门静脉高压症也很有用。在这一领域，ARFI弹性成像似乎不如TE。
