Department of diagnostic and interventional radiology, Saint-André Hospital, Bordeaux University Hospitals, 1, rue Jean-Burguet, 33075 Bordeaux, France.
Diagn Interv Imaging. 2013 May;94(5):515-34. doi: 10.1016/j.diii.2013.02.005. Epub 2013 Apr 24.
Conventional imaging techniques cannot provide information about tissue mechanical properties. Many injuries can cause changes in tissue stiffness, especially tumors and fibrosis. In recent years, various non-invasive ultrasound methods have been developed to study tissue elasticity for a large number of applications (breast, thyroid, prostate, kidneys, blood vessels, liver…). For non-invasive assessment of liver diseases, several ultrasound elastography techniques have been investigated: Transient elastography (the most extensively used), Real Time Elastography (RTE), Acoustic Radiation Force Impulse Imaging (ARFI) and more recently Shear Wave Elastography (SWE). Even if evaluation of liver fibrosis in chronic liver disease remains the principal application, there are many others applications for liver: predicting cirrhosis-related complications; monitoring antiviral treatments in chronic viral liver disease; characterizing liver tumors; monitoring local treatments, etc. The aim of this article is to report on the different hepatic ultrasound elastography techniques, their advantages and disadvantages, their diagnostic accuracy, their applications in clinical practice.
传统的成像技术无法提供组织力学特性的信息。许多损伤会导致组织硬度发生变化，尤其是肿瘤和纤维化。近年来，已经开发出各种非侵入性超声方法来研究组织弹性，用于大量应用（乳房、甲状腺、前列腺、肾脏、血管、肝脏等）。对于肝脏疾病的非侵入性评估，已经研究了几种超声弹性成像技术：瞬时弹性成像（应用最广泛）、实时弹性成像（RTE）、声辐射力脉冲成像（ARFI）以及最近的剪切波弹性成像（SWE）。尽管慢性肝病的肝纤维化评估仍然是主要应用，但肝脏还有许多其他应用：预测肝硬化相关并发症；监测慢性病毒性肝病的抗病毒治疗；描述肝脏肿瘤；监测局部治疗等。本文的目的是报告不同的肝脏超声弹性成像技术，它们的优缺点，它们的诊断准确性，它们在临床实践中的应用。
