Chung Mei, Wang Chenchen
Arthritis Res Ther. 2013;15(6):126. doi: 10.1186/ar4394.
Treatment of chronic pain conditions such as fibromyalgia is challenging due to limitations of drug therapies. An initial exploration into the relationships between self-reported alcohol consumption, symptom severity, and quality of life for individuals with fibromyalgia sheds new light on plausible hypotheses and potential mechanisms of action for future research. Evidence suggests that alcohol consumption may improve social and psychological factors because of activity in the ascending and descending pain pathways in modulating gamma-aminobutyric acid neurotransmission. Further methodologically rigorous studies in this field to improve well-being of individuals with fibromyalgia are warranted.
由于药物疗法存在局限性，治疗纤维肌痛等慢性疼痛病症具有挑战性。对纤维肌痛患者自我报告的饮酒量、症状严重程度和生活质量之间的关系进行的初步探索，为未来研究的合理假设和潜在作用机制提供了新的线索。有证据表明，饮酒可能会改善社会和心理因素，这是因为在调节γ-氨基丁酸神经传递的上行和下行疼痛通路中存在活动。有必要在该领域开展进一步方法严谨的研究，以改善纤维肌痛患者的健康状况。
