Hospital Medicine, Department of Internal Medicine, University of Missouri, One Hospital Drive, Columbia, MO 65212, USA; Diabetes and Cardiovascular Research Center, University of Missouri, One Hospital Drive, Columbia, MO 65212, USA.
Endocrinol Metab Clin North Am. 2013 Dec;42(4):789-808. doi: 10.1016/j.ecl.2013.06.002. Epub 2013 Aug 1.
In this article, the literature is reviewed regarding the role of blood pressure variability and nocturnal nondipping of blood pressure as well as the presence of diabetic kidney disease (DKD), in the absence of albuminuria, as risk predictors for progressive DKD. The importance of glycemic and blood pressure control in patients with diabetes and chronic kidney disease, and the use of oral hypoglycemic agents and antihypertensive agents in this patient cohort, are also discussed.
本文回顾了血压变异性和夜间血压非杓型以及在没有蛋白尿的情况下存在糖尿病肾脏疾病（DKD）作为进行性 DKD 的风险预测因子的文献。还讨论了血糖和血压控制在糖尿病和慢性肾脏病患者中的重要性，以及在这一患者群体中使用口服降糖药和抗高血压药的问题。
