美多心安的肝脏保护作用研究。
Study of hepatoprotective effects of xymedon.
作者信息
Vyshtakalyuk A B, Nazarov N G, Zueva I V, Lantsova A V, Minnekhanova O A, Busygin D V, Porfiryev A G, Evtyugin V G, Reznik V S, Zobov V V
机构信息
A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Research Center, Russian Academy of Sciences; Kazan (Volga Region) Federal University, Russia.
出版信息
Bull Exp Biol Med. 2013 Sep;155(5):643-6. doi: 10.1007/s10517-013-2215-0.
Xymedon (1-(β-oxyethyl)-4,6-dimethyl-1,2-dihydro-2-oxopyrimidine), a regeneratory and wound-healing drug, exhibited hepatoprotective activity in laboratory animals with experimental toxic hepatitis. Oral drug reduced the severity of toxic involvement of the liver induced by CCl4 and reduced animal mortality. Xymedon promoted recovery of the blood biochemical parameters characterizing the liver status.
西美顿（1-(β-羟乙基)-4,6-二甲基-1,2-二氢-2-氧代嘧啶）是一种具有再生和伤口愈合作用的药物，在患有实验性中毒性肝炎的实验动物中表现出肝脏保护活性。口服该药物可减轻由四氯化碳引起的肝脏中毒损伤的严重程度，并降低动物死亡率。西美顿促进了表征肝脏状态的血液生化参数的恢复。
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