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重症肌无力和胸腺瘤合并 1 型肌强直性营养不良。

Myasthenia gravis and thymoma coexisting with myotonic dystrophy type 1.

机构信息

Ege University School of Medicine, Neurology Department, Bornova Izmir, Turkey.

Ege University School of Medicine, Neurology Department, Bornova Izmir, Turkey.

出版信息

Neuromuscul Disord. 2014 Jan;24(1):40-2. doi: 10.1016/j.nmd.2013.09.001. Epub 2013 Sep 11.

Abstract

We describe a 34-year old man presenting with subacute generalized myasthenic symptoms. His clinical features and laboratory investigations demonstrated both myasthenia gravis and myotonic dystrophy type 1. The computerized tomography of chest revealed anterior mediastinal mass. The lymphocyte-rich thymoma was removed surgically and he received radiotherapy. Recent observations suggested that the patients with myotonic dystrophy may have an increased risk of benign and malignant tumours but its coexistence with thymoma is very rare. The risk of thymoma associated with myotonic dystrophy is unknown.

摘要

我们描述了一位 34 岁男性出现亚急性全身肌无力症状。他的临床特征和实验室检查结果同时显示患有重症肌无力和 1 型肌强直性营养不良。胸部计算机断层扫描显示前纵隔肿块。富含淋巴细胞的胸腺瘤被手术切除,他还接受了放疗。最近的观察结果表明,肌强直性营养不良患者可能有良性和恶性肿瘤的风险增加,但它与胸腺瘤共存非常罕见。与肌强直性营养不良相关的胸腺瘤的风险尚不清楚。

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