调节性T细胞与B细胞：对自身免疫性疾病的影响
Regulatory T cells and B cells: implication on autoimmune diseases.
作者信息
Wang Ping, Zheng Song Guo
机构信息
Division of Liver Transplantation Surgery, The First Affiliated Hospital of Nanjing Medical University 300 Guangzhou Road, Nanjing, 210029, China.
出版信息
Int J Clin Exp Pathol. 2013 Nov 15;6(12):2668-74. eCollection 2013.
Abstract
The regulatory T (Treg) cells play an important role in the maintenance of homeostasis and the prevention of autoimmune diseases. Although most studies are focusing on the role of Treg cells in T cells and T cells-mediated diseases, these cells also directly affect B cells and other non-T cells. This manuscript updates the role of Treg cells on the B cells and B cell-mediated diseases. In addition, the mechanisms whereby Treg cells suppress B cell responses have been discussed.
摘要
调节性T（Treg）细胞在维持体内平衡和预防自身免疫性疾病中发挥着重要作用。尽管大多数研究集中于Treg细胞在T细胞及T细胞介导的疾病中的作用，但这些细胞也直接影响B细胞和其他非T细胞。本文更新了Treg细胞在B细胞及B细胞介导的疾病中的作用。此外，还讨论了Treg细胞抑制B细胞反应的机制。
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