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中低强度激光治疗慢性耳鸣。

Medium-level laser in chronic tinnitus treatment.

机构信息

ENT Department, Regional Hospital, Endach 27, 6330 Kufstein, Austria.

出版信息

Biomed Res Int. 2013;2013:324234. doi: 10.1155/2013/324234. Epub 2013 Nov 5.

Abstract

The purpose of this study was to evaluate the effect of medium-level laser therapy in chronic tinnitus treatment. In a prospective double-blind placebo-controlled trial, either active laser (450 mW, 830 nm combined Ga-Al-As diode laser) or placebo irradiation was applied through the external acoustic meatus of the affected ear towards the cochlea. Fourty-eight patients with chronic tinnitus were studied. The main outcome was measured using the Goebel tinnitus questionnaire, visual analogue scales measuring the perceived loudness of tinnitus, the annoyance associated with tinnitus, and the degree of attention paid to tinnitus as well as psycho-acoustical matches of tinnitus pitch and loudness. The results did show only very moderate temporary improvement of tinnitus. Moreover, no statistically relevant differences between laser and placebo group could be found. We conclude that medium-level laser therapy cannot be regarded as an effective treatment of chronic tinnitus in our therapy regime considering the limited number of patients included in our study.

摘要

本研究旨在评估中能级激光疗法在慢性耳鸣治疗中的效果。采用前瞻性双盲安慰剂对照试验,通过受影响耳的外耳道将活性激光(450mW、830nm 组合 Ga-Al-As 二极管激光)或安慰剂照射到耳蜗。研究了 48 例慢性耳鸣患者。主要结局指标采用 Goebel 耳鸣问卷、测量耳鸣感知响度、耳鸣相关烦恼、对耳鸣关注程度的视觉模拟量表以及耳鸣音调和响度的心理声学匹配来衡量。结果仅显示出非常短暂的、中度的耳鸣改善。此外,激光组和安慰剂组之间没有发现统计学上的显著差异。我们的结论是,考虑到我们研究中纳入的患者数量有限,中能级激光疗法不能被视为慢性耳鸣的有效治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5772/3835591/864b0e8faecf/BMRI2013-324234.001.jpg

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