Division of Intramural Research, National Institute on Minority Health and Health Disparities, 3 Center Dr, Bldg 3, Rm 5W13, MSC 0311, Bethesda, MD 20892.
Hypertension. 2014 Jan;63(1):48-53. doi: 10.1161/HYPERTENSIONAHA.113.01629. Epub 2013 Dec 2.
Black men have higher blood pressure (BP) levels and consequently higher prevalence of hypertension compared with men from other ethnic groups in the United States. Socio-familial factors in childhood have been found to play an important role in hypertension, but few studies have examined this relationship among black men. We investigated whether childhood family living arrangements are independently associated with mean BP and hypertension in a cross-sectional sample of 515 unrelated black male participants aged ≥20 years enrolled in the Howard University Family Study between 2001 and 2008. Black men who lived with both parents compared with the reference group of men who never lived with both parents during their lifetime had lower systolic BP (-4.4 mm Hg [95% confidence interval {CI}, -7.84 to -0.96]), pulse pressure (-3.9 mm Hg [95% CI, -6.28 to -1.51]), and mean arterial BP (-2.0 mm Hg [95% CI, -4.44 to 0.51]). This protective effect was more pronounced among men who lived with both parents for 1 to 12 years of their lives; they had decreased systolic BP (-6.5 mm Hg [95% CI, -10.99 to -1.95]), pulse pressure (-5.4 mm Hg [95% CI, -8.48 to -2.28]), mean arterial pressure (-3.3 mm Hg [95% CI, -6.56 to 0.00]), and a 46% decreased odds of developing hypertension (odds ratio=0.54; 95% CI, 0.30 to 0.99). No statistically significant associations were found for diastolic BP. These results provide preliminary evidence that childhood family structure exerts a long-term influence on BP among black men.
黑人男性的血压水平高于其他族裔的男性,因此高血压的患病率也更高。研究发现,童年时期的社会家庭因素在高血压中起着重要作用,但很少有研究调查过黑人男性之间的这种关系。我们调查了在 2001 年至 2008 年间参加霍华德大学家庭研究的 515 名无血缘关系的 20 岁及以上黑人男性参与者的横断面样本中,童年时期的家庭生活安排是否与平均血压和高血压独立相关。与一生中从未与父母双方生活在一起的参考组相比,与父母双方一起生活的黑人男性收缩压(-4.4mmHg [95%置信区间 {CI},-7.84 至-0.96])、脉压(-3.9mmHg [95% CI,-6.28 至-1.51])和平均动脉压(-2.0mmHg [95% CI,-4.44 至 0.51])较低。这种保护作用在与父母双方一起生活 1 至 12 年的男性中更为明显;他们的收缩压(-6.5mmHg [95% CI,-10.99 至-1.95])、脉压(-5.4mmHg [95% CI,-8.48 至-2.28])和平均动脉压(-3.3mmHg [95% CI,-6.56 至 0.00])较低,且高血压的发病风险降低了 46%(比值比=0.54;95% CI,0.30 至 0.99)。舒张压无统计学显著相关性。这些结果初步表明,童年时期的家庭结构对黑人男性的血压有长期影响。