Vogel Markus, Schroten Horst, Kahl Philip, Müller Andreas
Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Hospital of Düsseldorf, Düsseldorf, Germany.
Neonatology. 2014;105(2):91-4. doi: 10.1159/000355538. Epub 2013 Nov 28.
We report a case of possible congenital tuberculosis in a 22+2 weeks, 460 g, vaginally delivered female infant born to a mother suffering from tuberculous endometritis, diagnosed soon after delivery. At 156 days of age, Mycobacterium tuberculosis was detected via PCR from the infant's gastric juice and was subsequently isolated. There was no evidence for horizontal transmission. Mother and child were treated successfully. This case illustrates the possibility of significant latency between infection and clinical manifestation in preterm infants and also emphasizes the need for urgent treatment of neonates in such situations.
我们报告了一例可能患有先天性结核病的病例，患儿为一名孕22⁺²周、体重460克、经阴道分娩的女婴，其母亲患有结核性子宫内膜炎，产后不久被诊断出来。在婴儿156日龄时，通过聚合酶链反应（PCR）从其胃液中检测到结核分枝杆菌，随后该菌被分离出来。没有水平传播的证据。母婴均得到成功治疗。该病例说明了早产儿感染与临床表现之间可能存在显著潜伏期，同时也强调了在此类情况下对新生儿进行紧急治疗的必要性。
