Rudén A K, Bäckman M, Bygdeman S, Jonsson A, Ringertz O, Sandström E
Acta Derm Venereol. 1986;66(4):325-33.
During one year 738 gonococcal isolates from 731 consecutive patients with gonorrhoea were collected and classified by co-agglutination using W I and W II/III specific monoclonal antibodies. Eight W I and 30 W II/III serovars (serovariants) were seen. In both serogroups the most frequent serovar among isolates from women and heterosexual men differed from that among isolates from homosexual men. Forty-two per cent of the serovars, were confined only to one subpopulation, i.e. women, heterosexual men or homosexual men, representing 19 (3%) of the 738 isolates. Out of these 19 isolates 42% were acquired abroad compared with 12% of the 653 isolates in the serovars shared between two or all three subpopulations (p less than 0.005). Imported W I isolates were often of the same serovar that dominated in Stockholm. W II/III isolates acquired abroad were often of unusual serovars (p less than 0.0005) and might be a source of future changes of the serovar pattern in Sweden. In this way we can follow the introduction of new serovars into our society and their circulation between the subpopulations.
在一年时间里,收集了731例连续淋病患者的738株淋球菌分离株,并使用W I和W II/III特异性单克隆抗体通过协同凝集进行分类。观察到8种W I血清型和30种W II/III血清型(血清变异型)。在这两个血清群中,女性和异性恋男性分离株中最常见的血清型与同性恋男性分离株中的不同。42%的血清型仅局限于一个亚群,即女性、异性恋男性或同性恋男性,占738株分离株中的19株(3%)。在这19株分离株中,42%是在国外获得的,而在两个或所有三个亚群共有的血清型中的653株分离株中这一比例为12%(p<0.005)。进口的W I分离株通常是在斯德哥尔摩占主导地位的相同血清型。在国外获得的W II/III分离株通常是不寻常的血清型(p<0.0005),可能是瑞典未来血清型模式变化的一个来源。通过这种方式,我们可以追踪新血清型引入我们的社会以及它们在亚群之间的传播情况。