利用深度二维图像和积分反射率来表示交叉极化光学相干断层扫描中脱矿质的严重程度。
Use of 2D images of depth and integrated reflectivity to represent the severity of demineralization in cross-polarization optical coherence tomography.
作者信息
Chan Kenneth H, Chan Andrew C, Fried William A, Simon Jacob C, Darling Cynthia L, Fried Daniel
机构信息
Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, 707 Parnassus Ave., San Francisco, CA 94143-0758, USA.
出版信息
J Biophotonics. 2015 Jan;8(1-2):36-45. doi: 10.1002/jbio.201300137. Epub 2013 Dec 5.
Abstract
Several studies have demonstrated the potential of cross-polarization optical coherence tomography (CP-OCT) to quantify the severity of early caries lesions (tooth decay) on tooth surfaces. The purpose of this study is to show that 2D images of the lesion depth and the integrated reflectivity can be used to accurately represent the severity of early lesions. Simulated early lesions of varying severity were produced on tooth samples using simulated lesion models. Methods were developed to convert the 3D CP-OCT images of the samples to 2D images of the lesion depth and lesion integrated reflectivity. Calculated lesion depths from OCT were compared with lesion depths measured from histological sections examined using polarized light microscopy. The 2D images of the lesion depth and integrated reflectivity are well suited for visualization of early demineralization.
摘要
多项研究已证明交叉极化光学相干断层扫描（CP - OCT）在量化牙齿表面早期龋损（蛀牙）严重程度方面的潜力。本研究的目的是表明，病变深度和积分反射率的二维图像可用于准确呈现早期病变的严重程度。使用模拟病变模型在牙齿样本上制作了不同严重程度的模拟早期病变。开发了将样本的三维CP - OCT图像转换为病变深度和病变积分反射率二维图像的方法。将光学相干断层扫描计算出的病变深度与使用偏振光显微镜检查的组织学切片测量的病变深度进行比较。病变深度和积分反射率的二维图像非常适合早期脱矿的可视化。
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