From the * Pain Clinic of Monterey Bay, Aptos; † Napa Pain Institute, CA; ‡ Neurosurgery Department, Palo Alto Medical Foundation, Santa Cruz; and §Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, CA.
Reg Anesth Pain Med. 2014 Jan-Feb;39(1):73-7. doi: 10.1097/AAP.0000000000000026.
We report 2 cases of spinal epidural hematoma formation after the removal of percutaneous spinal cord stimulator trial leads and discuss the possible etiologies of these complications.
Two patients developed spinal epidural hematomas shortly after removal of their percutaneous trial leads and required multilevel laminectomies for evacuation of the hematoma. Patient 1 reported taking aspirin the morning that his leads were pulled, whereas patient 2 had not taken aspirin in the 7 days before commencing his trial. There were 2 days between identification and evacuation of patient 1's hematoma, and he did not fully recover from the injury to his spinal cord. Patient 2 underwent surgery immediately with complete resolution of his symptoms.
Currently, the neuromodulation community ascribes to the American Society of Regional Anesthesia and Pain Medicine guidelines, which state that nonsteroidal anti-inflammatory drugs do not significantly increase the risk for epidural hematoma with neuraxial anesthesia and, therefore, there is no need to discontinue these drugs before epidural or spinal anesthesia. We suggest that these guidelines may not be appropriate for neuromodulatory techniques that likely subject the surrounding vasculature to more trauma than neuraxial anesthesia. We recommend discontinuing nonsteroidal anti-inflammatory drugs, particularly aspirin, before neuromodulation procedures. Further investigation will establish a timeframe for holding these drugs to optimize patient safety.
我们报告了 2 例经皮脊髓刺激试验导丝取出后形成脊髓硬膜外血肿的病例,并讨论了这些并发症的可能病因。
2 名患者在取出经皮试验导丝后不久即出现脊髓硬膜外血肿,需要进行多节段椎板切除术以清除血肿。患者 1 在拔除导丝的当天早上报告服用了阿司匹林,而患者 2 在开始试验前的 7 天内没有服用阿司匹林。患者 1 的血肿识别和清除之间相隔 2 天,他的脊髓损伤没有完全恢复。患者 2 立即进行了手术,症状完全缓解。
目前,神经调节领域遵循美国区域麻醉和疼痛医学学会的指南,该指南指出非甾体抗炎药不会显著增加椎管内麻醉后硬膜外血肿的风险,因此无需在硬膜外或脊髓麻醉前停用这些药物。我们认为,这些指南可能不适用于可能比椎管内麻醉对周围血管造成更大创伤的神经调节技术。我们建议在神经调节手术前停用非甾体抗炎药,特别是阿司匹林。进一步的研究将确定这些药物的停药时间,以优化患者的安全性。