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母鸡多次给予左甲状腺素后的反应。

Responses upon multiple administration of L-thyroxine in hens.

机构信息

Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Poland.

出版信息

Theor Appl Genet. 1979 May;54(3):121-8. doi: 10.1007/BF01159466.

DOI:10.1007/BF01159466
PMID:24310288
Abstract

Studies on the influence of repeated injections of L-thyroxine on enzyme activity and total protein level in the blood plasma of White Rock and Sussex hens have shown that: 1. The total protein level in both races decreased significantly. 2. Activity of aldolase increased in White Rock hens while in Sussex hens it increased considerably only after the last injection. 3. Activity of alanine aminotransferase did not change in White Rock hens and increased in the blood plasma of Sussex hens. 4. In both races, the activity of aspartate aminotransferase increased initially and changed after L-thyroxine injection. 5. Activity of alkaline phosphatase increased in White Rock hens, while in Sussex hens it decreased. 6. Statistically significant differences between activities of examined enzymes in both races after L-thyroxine administration were found.

摘要

对重复注射 L-甲状腺素对怀特洛克鸡和苏塞克斯鸡血浆中酶活性和总蛋白水平的影响的研究表明:1. 两个品种的总蛋白水平均显著下降。2. 醛缩酶活性在怀特洛克鸡中增加,而在苏塞克斯鸡中仅在最后一次注射后才显著增加。3. 丙氨酸氨基转移酶活性在怀特洛克鸡中没有变化,而在苏塞克斯鸡的血浆中增加。4. 在两个品种中,天冬氨酸氨基转移酶的活性最初增加,在注射 L-甲状腺素后发生变化。5. 碱性磷酸酶活性在怀特洛克鸡中增加,而在苏塞克斯鸡中则减少。6. 在给予 L-甲状腺素后,两个品种的酶活性有统计学意义的差异。

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2
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本文引用的文献

1
Mechanism of action of the thyroid hormone.甲状腺激素的作用机制。
Physiol Rev. 1951 Jul;31(3):205-43. doi: 10.1152/physrev.1951.31.3.205.
2
STUDIES ON THE EARLY EFFECTS OF THYROID HORMONES.甲状腺激素早期作用的研究
Endocrinology. 1965 Feb;76:323-8. doi: 10.1210/endo-76-2-323.
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COMPARATIVE EFFECTS OF VARIOUS ANALOGUES OF THYROXINE ON AMINO ACID INCORPORATION INTO PROTEIN.
Endocrinology. 1964 Sep;75:304-11. doi: 10.1210/endo-75-3-304.
4
Influence of exogenous thyroxine on live enzymes and glycogen and adrenal ascorbic acid in albino rats.外源性甲状腺素对白化大鼠肝脏酶、糖原及肾上腺抗坏血酸的影响。
Enzymologia. 1961 May 15;23:57-70.
5
A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.一种测定血清谷草转氨酶和谷丙转氨酶的比色法。
Am J Clin Pathol. 1957 Jul;28(1):56-63. doi: 10.1093/ajcp/28.1.56.
6
Biochemical and physiological differentiation during morphogenesis. XXI. Effect of hypothyroidism and hormone therapy on enzyme activities of the developing cerebral cortex of the rat.形态发生过程中的生化与生理分化。 XXI. 甲状腺功能减退及激素治疗对大鼠发育中大脑皮层酶活性的影响。
J Neurochem. 1957;1(3):279-88. doi: 10.1111/j.1471-4159.1957.tb12083.x.
7
[Determination and properties of the serumaldolase].[血清醛缩酶的测定及性质]
Biochem Z. 1954;325(2):156-62.
8
Effects of radiothyroidectomy and various replacement levels of thyroxine on growth, organ and gland weights of Cornish Cross chickens.甲状腺切除及不同甲状腺素替代水平对科尼什杂交鸡生长、器官及腺体重量的影响
Gen Comp Endocrinol. 1966 Dec;7(3):411-9. doi: 10.1016/0016-6480(66)90061-x.
9
A simplification of Kind and King's method for determination of serum phosphatase.一种简化的用于测定血清磷酸酶的金德方法。
Scand J Clin Lab Invest. 1966;18(3):353-6. doi: 10.3109/00365516609087208.
10
Interaction of thyroid hormone and androgen on body weight, comb, and liver in cockerels.甲状腺激素与雄激素对公鸡体重、鸡冠和肝脏的相互作用。
Gen Comp Endocrinol. 1966 Apr;6(2):276-87. doi: 10.1016/s0016-6480(66)80015-1.